Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. Randomized, Double-Blinded, Placebo-Controlled Crossover Pilot Study
LeBaron TW, Larson AJ, Ohta S, Mikami T, Barlow J, Bulloch J, DeBeliso M. · Journal of lifestyle medicine. 2019;9(1):36-43.
Study at a glance
Human
Human participants studied for exercise and recovery. See eligibility criteria in the linked full text.
Full text reports another explicitly administered H₂ intervention. Detected intervention quantities or schedules: 6.6 mM. · H₂-related quantities reported in the intervention passages: 6.6 mM. Values are not combined across different experimental arms.
Multiple article-specific time points; see the linked full methods.
Article-reported result excerpt (24 words maximum): “1 min) to end of exercise revealed that there was a significant decrease in the average HR for HRW compared to both the baseline…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
Human evidence; design, sample size and comparator limit interpretation. Funding or grant information is reported in the full article. No explicit conflict statement was identified in the machine-readable full article; absence is not inferred.
What kind of evidence is this?
Human
Randomized blinded controlled study
Exercise and recovery
Other forms
Information not yet classified
Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.
Methods
Human participants studied for exercise and recovery. See eligibility criteria in the linked full text.
Human study; the article does not state one consolidated sample total, so no total is inferred.
Multiple article-specific time points; see the linked full methods.
Full text reports another explicitly administered H₂ intervention. Detected intervention quantities or schedules: 6.6 mM.
another explicitly administered H₂ intervention — H₂ only unless the full text explicitly reports oxygen co-delivery.
H₂-related quantities reported in the intervention passages: 6.6 mM. Values are not combined across different experimental arms.
Placebo or matched control reported in the full article.
Outcomes and reported result
clinical symptoms or functional scores, oxidative-stress and antioxidant markers, apoptosis or cell injury, neurological or behavioral measures, respiratory measures
Article-reported result excerpt (24 words maximum): “1 min) to end of exercise revealed that there was a significant decrease in the average HR for HRW compared to both the baseline…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.
A reported association, difference or mechanism is not automatically a clinical benefit.
Limitations and applicability
Human evidence; design, sample size and comparator limit interpretation. Funding or grant information is reported in the full article. No explicit conflict statement was identified in the machine-readable full article; absence is not inferred.
Applies only to the population and protocol reported in this exercise and recovery article.
No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.
Sources and record status
PMID: 30918832 · DOI: 10.15280/jlm.2019.9.1.36
A free full article is available through PubMed Central.
Official PubMed/PMC full article; source identity, intervention data and declarations re-audited 25 August 2026.
25 August 2026
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