Independent research library

Molecular hydrogen (H2) research library

Explore 665 full-text-checked human, animal and laboratory studies on molecular hydrogen (H2), with methods, reported findings and limitations clearly separated.

665full-text-checked records

193human studies

472animal and laboratory records

How to interpret this libraryA study record reports what a source states and what was extracted from the complete available text. Inclusion is not proof of effectiveness, safety or clinical suitability. Human and preclinical evidence, clinical outcomes and biomarkers remain distinct.

665 matching records

HumanInhaled H₂2026

A randomized controlled double-blind study on the brain protection of infantile patients with epileptic spasm syndrome through atomized inhalation of hydrogen-oxygen gas

Chen C, He W, Chen J, Shi XY, Yang G, Wang J, Wang YY, Hu PL, Han F, Meng Y, Zou LP. · Frontiers in Neurology. 2026;17:1781738.

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HumanOther forms2026

Adjunctive Molecular Hydrogen Capsule Therapy in Empyema Complicated by Chronic Inflammatory Demyelinating Polyneuropathy: A Case Report

Li GL, Lu JW, Ho YJ, Lui SW, Hsieh TY, Wang KY, Liu FC. · In vivo (Athens, Greece). 2026;40(3):1832-1841.

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HumanOther forms2026

Adjunctive Molecular Hydrogen Therapy Modulates T Cell Markers and Reduces Anti-Ro Antibody in Refractory Oral Ulcers of Behçet’s Disease and Sjögren’s Syndrome: A Case Report

Lin CC, Lu JW, Ho YJ, Lui SW, Hsieh TY, Wang KY, Liu FC. · In vivo (Athens, Greece). 2026;40(2):1192-1200.

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HumanOther forms2026

Adjuvant Molecular Hydrogen Therapy in SLE-associated Pulmonary Arterial Hypertension: A Case Report on Immunomodulatory Effects on Regulatory and Effector Lymphocytes.

Liu C, Lu JW, Wu CH, Ho YJ, Lui SW, Hsieh TY, Wang KY, Liu FC. · In Vivo. 2026;40:14220.

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PreclinicalOther forms2026

Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model

Sakamoto K, Nakamura S, Tsuchiya T, Mitsuie T, Nakao Y, Htun Y, Yokota T, Inoue K, Inoue E, Wakabayashi T, Morimoto A, Koyano K, Konishi Y, Iwase T, Horii T, Kusaka T. · Scientific Reports. 2026;16:4344.

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HumanH₂-rich water2026

Association of self-selected hydrogen-rich water consumption with 6-month changes in chair-stand performance and gait speed among community-dwelling older adults attending community salons

Harada Y, Miyakawa M. · Journal of Frailty, Sarcopenia and Falls. 2026;11(2):137–143.

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PreclinicalInhaled H₂2026

Comparison of hydrogen administration methods in the treatment of radiation-induced heart disease in rats

Kura B, Pavelkova P, Kalocayova B, Sykora M, Vlkovicova J, Kluknavsky M, LeBaron T, Pobijakova M, Sagatova A, Slezak J. · Can J Physiol Pharmacol. 2026;104:1–13.

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HumanInhaled H₂2026

Effect of hydrogen–oxygen inhalation on sleep disorders and abnormal mood: a single-blind, randomized controlled trial

Gao YH et al. · Med Gas Res. 2026;16(2):98–102.

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HumanOther forms2026

Effects of Hydrogen Water Gargling on Oral Mucositis and Pain in Head and Neck Cancer Patients: A Randomized Controlled Pilot Study

Tsai HT et al. · Integr Cancer Ther. 2026;25:15347354261463550.

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HumanH₂-rich water2026

Effects of Hydrogen-Rich Water Supplementation on Exercise Performance, Autonomic Nervous System Recovery, and Blood Lactate Concentration During Repeated Sprint Exercise in Male University Athletes

Chen Z, Chi M, Liu R, Ma L, Shen Y. · Journal of Sports Science and Medicine. 2026;25:744–752.

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PreclinicalOther forms2026

Efficacy of silicon-based agent against aging-related frailty.

Koyama Y, Kobayashi Y, Kobayashi H, Shimada S. · Scientific Reports. 2026;16:39711.

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PreclinicalH₂-rich water2026

Electrolyzed Hydrogen Water Improves Chemosensitivity to Anticancer Drugs by Potently Suppressing Autophagy

Yano S, Xie L, Li J, Sugaya Y, Miyauchi Y, Kabayama S, Hara T. · Journal of cellular and molecular medicine. 2026;30(4):e71011.

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HumanH₂-rich water2026

Hydration bioanalyses of the effects of hydrogen-rich water (HRW)

Pesotskaya LA, Ignatov II, Popova TP, Huether F, Ignatov AI. · Wiad Lek. 2026;79(4):690–699.

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PreclinicalOther forms2026

Hydrogen gas (H_2) pretreatment improves lipopolysaccharide-induced acute liver injury in mice by inhibiting NLRP3 inflammasome activation and pyroptosis signaling

Chen X, Suo W, Li Q, Chen Y, Deng Y, Xu L, Dai J, Zhang N, Xu J, Xu J, Zhang X, Su W, Lu C, Yang S, Yang H, Zhu H, Liu H, Guo W, Zhang Y. · Frontiers in immunology. 2026;17:1759535.

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PreclinicalOther forms2026

Hydrogen Gas Therapy in Schizophrenia: Potential Neuroprotective Effects From an Animal Study

Miyake N, Haga T, Hirano SI, Ichikawa Y, Oguchi Y, Ando K. · Neuropsychopharmacology reports. 2026;46(2):e70117.

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PreclinicalOther forms2026

Hydrogen gas with hypothermic machine perfusion induces lipidomic alterations in donation-after-cardiac-death rat livers

Minami Y, Gowda SGBB, Shibata K, Sakamoto S, Gowda D, Shimamura T, Taketomi A, Chiba H, Fukai M, Hui SP. · Journal of Lipid Research. 2026;67(6):101040.

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PreclinicalInhaled H₂2026

Hydrogen improves the efficacy of tetrandrine in the treatment of silicosis by inhibiting vascular endothelial mesenchymal transition caused by oxidative stress

Xiao K, Li M, Mu Y, Sun Y, Wang S, Chen S, Ma J, Cao M, Yang Y, Shao H, Ding X, Cui G, Du Z. · Frontiers in Bioengineering and Biotechnology. 2026;13:1668524.

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HumanInhaled H₂2026

Hydrogen inhalation is associated with a transient rightward shift in prefrontal oxyhemoglobin asymmetry and autonomic modulation

Moriya M, Oyama K, Den Y, Yamada Y, Sakatani K. · Scientific reports. 2026;16(1):6202.

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PreclinicalOther forms2026

Hydrogen-generating nanomodulators for metabolic repair and functional recovery in ovarian tissue transplantation

Jiang M, Liu J, Zhao Y, Bai X, Yan H, Zeng Q, Wang L, Liao Y, Xiong D, Xie H, Luan Z, Yu L, He L, Zhou Z, Zhang G, Miao YB, Liu W. · Journal of nanobiotechnology. 2026;24(1):260.

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PreclinicalOther forms2026

Hydrogen-rich saline treatment modulates proteomic profiles to mitigate cataract development in a N-methyl-N-nitrosourea-induced rat model

Qu Y, Li X, Yang Q, Li R, Tao Y, Huang Y, Wang L. · International ophthalmology. 2026;46(1):63.

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PreclinicalH₂-rich water2026

Hydrogen-rich water alleviates neuropathic pain through the modulation of bile acid/Takeda G-protein-coupled receptor 5-mediated autophagy

Zeng X et al. · Pain. 2026;167(3):663–677.

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HumanH₂-rich water2026

Hydrogen-Rich Water as a Performance-Enhancing Aid in National-Level Finswimmers: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

Sládečková B et al. · Int J Sports Physiol Perform. 2026;21(7):824–830.

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PreclinicalH₂-rich water2026

Hydrogen-rich water improves endurance by reducing skeletal muscle oxidative stress and inflammatory responses

Mizuno E et al. · Front Nutr. 2026;13:1722091.

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PreclinicalOther forms2026

Hydrogen‐Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy

Xu Z, Cui X, Chu H, Wan H, Xie Y, Wang Y, Ni Q, Ding X, Song G. · Journal of diabetes. 2026;18(4):e70209.

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