Hydrogenology
Hydrogenology editorial study record

Short-term H_2 inhalation improves running performance and torso strength in healthy adults

Javorac D, Stajer V, Ratgeber L, Betlehem J, Ostojic S. · Biology of sport. 2019;36(4):333-339.

HumanInhaled H₂Published 2019
Study record, not medical adviceThis page reports one source and Hydrogenology’s source-text extraction. It does not establish that molecular hydrogen is effective, safe or appropriate for any person. Human, animal and laboratory evidence must not be treated as equivalent.
Source and classification

What kind of evidence is this?

Evidence stream

Human

Reported design

Randomized blinded controlled study

Research topic

Exercise and recovery

Administration classification

Inhaled H₂

Study result signal

Not reported in this record.

Outcome type

Not reported in this record.

Reported in the source

Methods at a glance

Population or model

Human participants studied for exercise and recovery. See eligibility criteria in the linked full text.

Sample

Human study; group or assay counts reported in the full text include n=20.

Duration

7 days

Intervention

Full text reports inhaled H₂-containing gas. Detected intervention quantities or schedules: 4%, 7 days, 60 min, 4 weeks, 45 mL/min.

Hydrogen form

Inhaled molecular H₂; not classified as Brown’s gas without an H₂/O₂ composition.

H₂ specification

H₂-related quantities reported in the intervention passages: 4%, 7 days, 60 min, 4 weeks, 45 mL/min. Values are not combined across different experimental arms.

H₂ flow

Not reported in the full article — an absolute H₂ flow in mL/min could not be verified.

O₂ delivered with H₂

O₂ concentration and absolute O₂ flow were not both reported in the full article; no value is inferred.

Comparator

Placebo or matched control reported in the full article.

Reported, not endorsed

Outcomes and reported result

Outcomes measured

survival or mortality, clinical symptoms or functional scores, oxidative-stress and antioxidant markers, apoptosis or cell injury, metabolic laboratory measures, cardiovascular measures

Reported result

Article-reported result excerpt (24 words maximum): “Baseline CRP levels were decreased by 1.0 mg/L (95% CI; 0.6–1.4) and by 0.7 mg/L (95% CI; 0.3–1.2) after hydrogen and placebo inhalation at…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.

Results-extraction completeness

The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.

A reported association, difference or mechanism is not automatically a clinical benefit. Null findings, outcome type, study design and precision all matter.

Interpretation limits

Cautions and applicability

Design and reporting cautions

Human evidence; design, sample size and comparator limit interpretation. No funding statement was identified in the machine-readable full article; absence is not inferred. No explicit conflict statement was identified in the machine-readable full article; absence is not inferred.

Applies directly to

Applies only to the population and protocol reported in this exercise and recovery article.

Preliminary appraisal framework

Not reported in this record.

Preliminary risk-of-bias status

Not reported in this record.

Appraisal rationale

Not reported in this record.

No single-study GRADE certainty rating is assigned. Certainty is assessed by important outcome across a complete eligible evidence set, not by attaching a final grade to one source.

Provenance

Sources and record status

Identifiers

PMID: 31938004 · DOI: 10.5114/biolsport.2019.88756

Publisher access

A free full article is available through PubMed Central.

Extraction basis

Official Europe PMC JATS full article and PubMed/PMC identifiers; structured full-text extraction and validation completed 8 August 2026.

Record revision

2026-08-10