Hydrogen-rich water suppresses the reduction in blood total antioxidant capacity induced by 3 consecutive days of severe exercise in physically active males
Dobashi S et al. · Med Gas Res. 2020;10(1):21–26.
Study at a glance
Human
Healthy physically active young men
500 mL hydrogen-rich water within 5 minutes before exercise and another 500 mL after exercise on each of 3 consecutive days · 5.14 ± 0.03 ppm dissolved H₂ immediately before drinking.
Three consecutive exercise days in each condition, with at least a 1-week crossover interval
Exercise-performance and lactate outcomes did not differ between water conditions. The H₂-water condition attenuated the reduction in the BAP/d-ROM redox ratio observed across consecutive exercise days, but baseline imbalance complicated interpretation.
Only eight men, single blinding, no performance decrement induced by the protocol, and an unexpected baseline difference in the main redox ratio. The manufacturer supplied the hydrogen-generating kits.
What kind of evidence is this?
Human
Randomized single-blind controlled crossover repeated-measures study
Exercise and recovery
H₂-rich water
Information not yet classified
Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.
Methods
Healthy physically active young men
8 participants
Three consecutive exercise days in each condition, with at least a 1-week crossover interval
500 mL hydrogen-rich water within 5 minutes before exercise and another 500 mL after exercise on each of 3 consecutive days
H₂ dissolved in water — H₂ only, not Brown’s gas.
5.14 ± 0.03 ppm dissolved H₂ immediately before drinking.
Placebo tap water with 0.00 ± 0.00 ppm H₂, prepared in a similar container
Outcomes and reported result
Countermovement jump, knee-extensor strength, sprint-cycling power, lactate and serum redox markers
Exercise-performance and lactate outcomes did not differ between water conditions. The H₂-water condition attenuated the reduction in the BAP/d-ROM redox ratio observed across consecutive exercise days, but baseline imbalance complicated interpretation.
Preparation, dose, outcome tables, limitations and disclosures checked in the open-access full text; independent appraisal remains incomplete.
A reported association, difference or mechanism is not automatically a clinical benefit.
Limitations and applicability
Only eight men, single blinding, no performance decrement induced by the protocol, and an unexpected baseline difference in the main redox ratio. The manufacturer supplied the hydrogen-generating kits.
Healthy physically active young men completing the reported 3-day sprint-cycling protocol.
No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.
Sources and record status
PMID: 32189665 · DOI: 10.4103/2045-9912.279979
Open-access full text is available through PMC.
Open-access PMC full text, PubMed record and CiNii bibliographic record.
10 August 2026
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