The Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme Q_10 Levels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease
Sumbalová Z, Kucharská J, Rausová Z, Gvozdjáková A, Szántová M, Kura B, Mojto V, Slezák J. · International journal of molecular sciences. 2023;24(15):12477.
Study at a glance
Human
Human participants studied for liver health. See eligibility criteria in the linked full text.
Full text reports H₂ dissolved in drinking water plus H₂ dissolved in saline. Detected intervention quantities or schedules: 330 mL, 8 weeks. · H₂-related quantities reported in the intervention passages: 330 mL, 8 weeks. Values are not combined across different experimental arms.
8 weeks
Article-reported result excerpt (24 words maximum): “In the H_2 group, this parameter was significantly lower at baseline when compared to the control group (−11.4%, p = 0.007), and it increased…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
Human evidence; design, sample size and comparator limit interpretation. Funding or grant information is reported in the full article. The article declares no conflicts of interest.
What kind of evidence is this?
Human
Randomized blinded controlled study
Liver health
H₂-rich water
Information not yet classified
Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.
Methods
Human participants studied for liver health. See eligibility criteria in the linked full text.
Human study; the full text reports 30 patients, with group/assay counts including n=57.
8 weeks
Full text reports H₂ dissolved in drinking water plus H₂ dissolved in saline. Detected intervention quantities or schedules: 330 mL, 8 weeks.
H₂ dissolved in drinking water plus H₂ dissolved in saline — H₂ only unless the full text explicitly reports oxygen co-delivery.
H₂-related quantities reported in the intervention passages: 330 mL, 8 weeks. Values are not combined across different experimental arms.
Placebo or matched control reported in the full article.
Outcomes and reported result
survival or mortality, clinical symptoms or functional scores, tumor growth or cancer markers, inflammation and cytokines, oxidative-stress and antioxidant markers, apoptosis or cell injury
Article-reported result excerpt (24 words maximum): “In the H_2 group, this parameter was significantly lower at baseline when compared to the control group (−11.4%, p = 0.007), and it increased…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.
A reported association, difference or mechanism is not automatically a clinical benefit.
Limitations and applicability
Human evidence; design, sample size and comparator limit interpretation. Funding or grant information is reported in the full article. The article declares no conflicts of interest.
Applies only to the population and protocol reported in this liver health article.
No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.
Sources and record status
PMID: 37569850 · DOI: 10.3390/ijms241512477
A free full article is available through PubMed Central.
Official PubMed/PMC full article; source identity, intervention data and declarations re-audited 25 August 2026.
29 September 2026
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