Hydrogenology
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Effects of 8 days intake of hydrogen-rich water on muscular endurance performance and fatigue recovery during resistance training

Zhou K et al. · Front Physiol. 2024;15:1458882.

HumanH₂-rich waterPublished 2024Source checked
Study record, not medical adviceThis record reports what the source states. It is not medical advice and does not establish that molecular hydrogen is effective, safe or appropriate for any person.
Quick summary

Study at a glance

Evidence type

Human

Population or model

Healthy trained male university students performing resistance training at least three times per week

Intervention and dose

1,920 mL/day for 7 days, then 1,260 mL divided before, during and after the resistance-training session on day 8 · 1,600 ppb dissolved H₂ according to the device manufacturer; reported pH 7.9, oxidation-reduction potential 650 mV as printed in the accessible text (sign not shown), and temperature 22°C.

Duration

Eight-day intake period in each condition, 1-week crossover washout and recovery measurements through 48 hours

Reported result

Total half-squat power (50,866.7 vs 46,431.0 W; p=0.032) and total repetitions (78.2 vs 70.3; p=0.019) were higher with H₂ water. Countermovement jump, perceived recovery and muscle-soreness outcomes did not significantly differ.

Main limitation

Small male-only crossover study, short intervention and many outcomes. The H₂ concentration was reported from manufacturer information rather than an independent measurement. Authors declared no commercial conflicts; university funding was reported.

Evidence and classification

What kind of evidence is this?

Evidence type

Human

Reported design

Randomized double-blind placebo-controlled crossover study

Research topic

Exercise and recovery

Administration form

H₂-rich water

Information not yet classified

Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.

Reported in the source

Methods

Population or model

Healthy trained male university students performing resistance training at least three times per week

Sample

18 participants

Duration

Eight-day intake period in each condition, 1-week crossover washout and recovery measurements through 48 hours

Intervention

1,920 mL/day for 7 days, then 1,260 mL divided before, during and after the resistance-training session on day 8

Hydrogen form

H₂ dissolved in water — H₂ only, not Brown’s gas.

Dose or H₂ specification

1,600 ppb dissolved H₂ according to the device manufacturer; reported pH 7.9, oxidation-reduction potential 650 mV as printed in the accessible text (sign not shown), and temperature 22°C.

Comparator

Purified placebo water matched in appearance, taste and odor

Reported, not endorsed

Outcomes and reported result

Outcomes measured

Half-squat power and repetitions to failure, countermovement jump, perceived recovery and muscle soreness

Reported result

Total half-squat power (50,866.7 vs 46,431.0 W; p=0.032) and total repetitions (78.2 vs 70.3; p=0.019) were higher with H₂ water. Countermovement jump, perceived recovery and muscle-soreness outcomes did not significantly differ.

Extraction completeness

Intervention, full outcome tables, funding and conflict statement checked in the open-access publisher full text; independent appraisal remains incomplete.

A reported association, difference or mechanism is not automatically a clinical benefit.

Interpretation limits

Limitations and applicability

Main methodological cautions

Small male-only crossover study, short intervention and many outcomes. The H₂ concentration was reported from manufacturer information rather than an independent measurement. Authors declared no commercial conflicts; university funding was reported.

Applies directly to

Young resistance-trained men performing six sets of half squats to failure at 70% of one-repetition maximum.

No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.

Sources and status

Sources and record status

Identifiers

PMID: 39434721 · DOI: 10.3389/fphys.2024.1458882

Publisher access

Open-access publisher and PMC full texts are available.

Extraction basis

Open-access Frontiers and PMC full texts plus PubMed bibliographic record.

Last reviewed

10 August 2026

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