Hydrogenology
Hydrogenology editorial study record

Effects of 8 days intake of hydrogen-rich water on muscular endurance performance and fatigue recovery during resistance training

Zhou K et al. · Front Physiol. 2024;15:1458882.

HumanH₂-rich waterPublished 2024
Study record, not medical adviceThis page reports one source and Hydrogenology’s source-text extraction. It does not establish that molecular hydrogen is effective, safe or appropriate for any person. Human, animal and laboratory evidence must not be treated as equivalent.
Source and classification

What kind of evidence is this?

Evidence stream

Human

Reported design

Randomized double-blind placebo-controlled crossover study

Research topic

Exercise and recovery

Administration classification

H₂-rich water

Study result signal

Not reported in this record.

Outcome type

Not reported in this record.

Reported in the source

Methods at a glance

Population or model

Healthy trained male university students performing resistance training at least three times per week

Sample

18 participants

Duration

Eight-day intake period in each condition, 1-week crossover washout and recovery measurements through 48 hours

Intervention

1,920 mL/day for 7 days, then 1,260 mL divided before, during and after the resistance-training session on day 8

Hydrogen form

H₂ dissolved in water — H₂ only, not Brown’s gas.

H₂ specification

1,600 ppb dissolved H₂ according to the device manufacturer; reported pH 7.9, oxidation-reduction potential 650 mV as printed in the accessible text (sign not shown), and temperature 22°C.

H₂ flow

Not applicable — oral water, not gas inhalation.

O₂ delivered with H₂

No O₂ was co-delivered as part of the intervention.

Comparator

Purified placebo water matched in appearance, taste and odor

Reported, not endorsed

Outcomes and reported result

Outcomes measured

Half-squat power and repetitions to failure, countermovement jump, perceived recovery and muscle soreness

Reported result

Total half-squat power (50,866.7 vs 46,431.0 W; p=0.032) and total repetitions (78.2 vs 70.3; p=0.019) were higher with H₂ water. Countermovement jump, perceived recovery and muscle-soreness outcomes did not significantly differ.

Results-extraction completeness

Intervention, full outcome tables, funding and conflict statement checked in the open-access publisher full text; independent appraisal remains incomplete.

A reported association, difference or mechanism is not automatically a clinical benefit. Null findings, outcome type, study design and precision all matter.

Interpretation limits

Cautions and applicability

Design and reporting cautions

Small male-only crossover study, short intervention and many outcomes. The H₂ concentration was reported from manufacturer information rather than an independent measurement. Authors declared no commercial conflicts; university funding was reported.

Applies directly to

Young resistance-trained men performing six sets of half squats to failure at 70% of one-repetition maximum.

Preliminary appraisal framework

Not reported in this record.

Preliminary risk-of-bias status

Not reported in this record.

Appraisal rationale

Not reported in this record.

No single-study GRADE certainty rating is assigned. Certainty is assessed by important outcome across a complete eligible evidence set, not by attaching a final grade to one source.

Provenance

Sources and record status

Identifiers

PMID: 39434721 · DOI: 10.3389/fphys.2024.1458882

Publisher access

Open-access publisher and PMC full texts are available.

Extraction basis

Open-access Frontiers and PMC full texts plus PubMed bibliographic record.

Record revision

2026-08-10