Morphofunctional characteristics of the liver and kidneys of Chinchilla lanigera during consumption of water enriched with molecular hydrogen
Panina EV, Karkishchenko VN, Ostrenko KS, Petrov DV, Sorochan AE. · Journal Biomed. 2024;20(3E):70–76.
What kind of evidence is this?
Preclinical
Controlled long-duration animal study
Liver health
H₂-rich water
Mixed exploratory preclinical signal.
Long-term organ morphology and laboratory outcomes in animals.
Methods at a glance
Chinchilla lanigera maintained under the reported laboratory conditions.
20 chinchillas.
Three years.
Water enriched with molecular hydrogen.
H₂ dissolved in drinking water.
The checked article reports preparation and monitoring; see the linked full text.
Not applicable — drinking water.
No oxygen was co-delivered.
Animals receiving standard water.
Outcomes and reported result
Liver and kidney morphology and functional laboratory measures.
The article reports group differences in selected liver and kidney measures after long-term exposure.
The full article methods, intervention, outcomes, positive and null findings, funding and conflict statements were checked.
A reported association, difference or mechanism is not automatically a clinical benefit. Null findings, outcome type, study design and precision all matter.
Cautions and applicability
Small, long-duration animal study with limited reporting of randomization and blinding.
Chinchillas under the reported husbandry and exposure conditions.
SYRCLE animal-study tool — preliminary
High risk
Allocation, handling differences, attrition and blinded assessment were not fully established.
Sequence generation checked where reported · Allocation concealment generally unclear · Personnel blinding generally unclear · Outcome-assessor blinding generally unclear · No prospectively registered analysis plan identified
No single-study GRADE certainty rating is assigned. Certainty is assessed by important outcome across a complete eligible evidence set, not by attaching a final grade to one source.
Sources and record status
DOI: 10.33647/2713-0428-20-3E-70-76 · DOI: 10.33647/2713-0428-20-3E-70-76
A free publisher or repository full article was checked.
Publisher or repository full article and bibliographic record; checked 10 August 2026.
2026-08-10