Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats
Yan W, Chen T, Long P, Zhang Z, Liu Q, Wang X, An J, Zhang Z. · Medical science monitor : international medical journal of experimental and clinical research. 2018;24:3840-3847.
Study at a glance
Preclinical
rats, cells, rat, rabbit used to study eye health.
Full text reports inhaled H₂-containing gas. Detected intervention quantities or schedules: 67%, 33%, 3 L/min. · H₂-related quantities reported in the intervention passages: 67%, 33%, 3 L/min. Values are not combined across different experimental arms.
3 L/min
Article-reported result excerpt (24 words maximum): “Post-treatment hydrogen gas inhalation did not ameliorate the clinical signs, or reduce the infiltrating cells of EIU.” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
Preclinical evidence only; findings do not establish a treatment effect in people. Funding or grant information is reported in the full article. The full article contains a conflict, commercial-support or supplied-product declaration; consult the source wording.
What kind of evidence is this?
Preclinical
Controlled animal and cell study
Eye health
Inhaled H₂
Information not yet classified
Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.
Methods
rats, cells, rat, rabbit used to study eye health.
Preclinical study; the full text reports 36 rats.
3 L/min
Full text reports inhaled H₂-containing gas. Detected intervention quantities or schedules: 67%, 33%, 3 L/min.
Inhaled molecular H₂ at 67%; oxygen co-delivery is reported.
H₂-related quantities reported in the intervention passages: 67%, 33%, 3 L/min. Values are not combined across different experimental arms.
2010 mL/min H₂, calculated from 67% H₂ and 3000 mL/min total flow reported in the full text.
33% O₂; 990 mL/min O₂ calculated from the reported total flow.
Control or comparison condition reported in the full article; see the linked methods for arm-specific details.
Outcomes and reported result
clinical symptoms or functional scores, tumor growth or cancer markers, inflammation and cytokines, oxidative-stress and antioxidant markers, apoptosis or cell injury, metabolic laboratory measures
Article-reported result excerpt (24 words maximum): “Post-treatment hydrogen gas inhalation did not ameliorate the clinical signs, or reduce the infiltrating cells of EIU.” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.
A reported association, difference or mechanism is not automatically a clinical benefit.
Limitations and applicability
Preclinical evidence only; findings do not establish a treatment effect in people. Funding or grant information is reported in the full article. The full article contains a conflict, commercial-support or supplied-product declaration; consult the source wording.
Applies to the reported animal, cell or tissue model, not directly to patients.
No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.
Sources and record status
PMID: 29875353 · DOI: 10.12659/msm.907269
A free full article is available through PubMed Central.
Official Europe PMC JATS full article and PubMed/PMC identifiers; structured full-text extraction and validation completed 8 August 2026.
10 August 2026
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