Hydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo
Li H, Yin Y, Liu J, Lu B, Wan H, Yang L, Wang W, Li R. · Journal of radiation research. 2021;62(1):34-45.
Study at a glance
Preclinical
cell, mice, mouse, cells used to study metabolic and lipid health.
Full text reports H₂ dissolved in drinking water. Detected intervention quantities or schedules: 1 mM, 0.4 mL, 14 days, 10 min, 7 days, 10 μM, 30 min, 5 μM, 40 min, 60 min. · H₂-related quantities reported in the intervention passages: 1 mM, 0.4 mL, 14 days, 10 min, 7 days, 10 μM, 30 min, 5 μM, 40 min, 60 min. Values are not combined across different experimental arms.
14 days
Article-reported result excerpt (24 words maximum): “However, mice treated with additional HRW (HRW + HTO groups) exhibited significant higher urinary radioactivity compared to other groups within 3 days after HTO…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
Preclinical evidence only; findings do not establish a treatment effect in people. Funding or grant information is reported in the full article. The full article contains a conflict, commercial-support or supplied-product declaration; consult the source wording.
What kind of evidence is this?
Preclinical
Randomized controlled study
Metabolic and lipid health
H₂-rich water
Information not yet classified
Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.
Methods
cell, mice, mouse, cells used to study metabolic and lipid health.
Preclinical study; group or assay counts reported in the full text include n=20.
14 days
Full text reports H₂ dissolved in drinking water. Detected intervention quantities or schedules: 1 mM, 0.4 mL, 14 days, 10 min, 7 days, 10 μM, 30 min, 5 μM, 40 min, 60 min.
H₂ dissolved in drinking water — H₂ only unless the full text explicitly reports oxygen co-delivery.
H₂-related quantities reported in the intervention passages: 1 mM, 0.4 mL, 14 days, 10 min, 7 days, 10 μM, 30 min, 5 μM, 40 min, 60 min. Values are not combined across different experimental arms.
Control or comparison condition reported in the full article; see the linked methods for arm-specific details.
Outcomes and reported result
survival or mortality, oxidative-stress and antioxidant markers, apoptosis or cell injury, metabolic laboratory measures, respiratory measures
Article-reported result excerpt (24 words maximum): “However, mice treated with additional HRW (HRW + HTO groups) exhibited significant higher urinary radioactivity compared to other groups within 3 days after HTO…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.
A reported association, difference or mechanism is not automatically a clinical benefit.
Limitations and applicability
Preclinical evidence only; findings do not establish a treatment effect in people. Funding or grant information is reported in the full article. The full article contains a conflict, commercial-support or supplied-product declaration; consult the source wording.
Applies to the reported animal, cell or tissue model, not directly to patients.
No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.
Sources and record status
PMID: 33231266 · DOI: 10.1093/jrr/rraa104
A free full article is available through PubMed Central.
Official PubMed/PMC full article; source identity, intervention data and declarations re-audited 25 August 2026.
25 August 2026
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