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Source-linked study record

A green, efficient and precise hydrogen therapy of cancer based on in vivo electrochemistry

Qi G, Wang B, Song X, Li H, Jin Y. · National science review. 2020;7(3):660-670.

PreclinicalOther formsPublished 2020Source checked
Study record, not medical adviceThis record reports what the source states. It is not medical advice and does not establish that molecular hydrogen is effective, safe or appropriate for any person.
Quick summary

Study at a glance

Evidence type

Preclinical

Population or model

cell, cells, mice, mouse used to study brain tumors — glioma and glioblastoma.

Intervention and dose

Full text reports an injected or infused H₂ intervention. Detected intervention quantities or schedules: 3 days, 12 days, 10%, 5%. · H₂-related quantities reported in the intervention passages: 3 days, 12 days, 10%, 5%. Values are not combined across different experimental arms.

Duration

3 days

Reported result

Article-reported result excerpt (24 words maximum): “The results showed that the more acidic the solution, the more H_2 was produced (Fig. [1]D).” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.

Main limitation

Preclinical evidence only; findings do not establish a treatment effect in people. Funding or grant information is reported in the full article. The full article contains a conflict, commercial-support or supplied-product declaration; consult the source wording.

Evidence and classification

What kind of evidence is this?

Evidence type

Preclinical

Reported design

Controlled animal and cell study

Research topic

Brain tumors — glioma and glioblastoma

Administration form

Other forms

Information not yet classified

Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.

Reported in the source

Methods

Population or model

cell, cells, mice, mouse used to study brain tumors — glioma and glioblastoma.

Sample

Preclinical study; group or assay counts reported in the full text include n=3.

Duration

3 days

Intervention

Full text reports an injected or infused H₂ intervention. Detected intervention quantities or schedules: 3 days, 12 days, 10%, 5%.

Hydrogen form

an injected or infused H₂ intervention — H₂ only unless the full text explicitly reports oxygen co-delivery.

Dose or H₂ specification

H₂-related quantities reported in the intervention passages: 3 days, 12 days, 10%, 5%. Values are not combined across different experimental arms.

Comparator

Control or comparison condition reported in the full article; see the linked methods for arm-specific details.

Reported, not endorsed

Outcomes and reported result

Outcomes measured

survival or mortality, clinical symptoms or functional scores, tumor growth or cancer markers, apoptosis or cell injury

Reported result

Article-reported result excerpt (24 words maximum): “The results showed that the more acidic the solution, the more H_2 was produced (Fig. [1]D).” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.

Extraction completeness

The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.

A reported association, difference or mechanism is not automatically a clinical benefit.

Interpretation limits

Limitations and applicability

Main methodological cautions

Preclinical evidence only; findings do not establish a treatment effect in people. Funding or grant information is reported in the full article. The full article contains a conflict, commercial-support or supplied-product declaration; consult the source wording.

Applies directly to

Applies to the reported animal, cell or tissue model, not directly to patients.

No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.

Sources and status

Sources and record status

Identifiers

PMID: 34692085 · DOI: 10.1093/nsr/nwz199

Publisher access

A free full article is available through PubMed Central.

Extraction basis

Official Europe PMC JATS full article and PubMed/PMC identifiers; structured full-text extraction and validation completed 8 August 2026.

Last reviewed

10 August 2026

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