Effect of Hydrogen Inhalation Therapy on Hearing Loss of Patients With Nasopharyngeal Carcinoma After Radiotherapy
Kong X, Lu T, Lu YY, Yin Z, Xu K. · Frontiers in medicine. 2022;9:828370.
Study at a glance
Human
Human participants studied for other neurological conditions. See eligibility criteria in the linked full text.
Full text reports inhaled H₂-containing gas. Detected intervention quantities or schedules: 4 weeks, 2.0 L/min, 1.0 L/min, 3 days, 12 weeks, 8 weeks. · H₂-related quantities reported in the intervention passages: 4 weeks, 2.0 L/min, 1.0 L/min, 3 days, 12 weeks, 8 weeks. Values are not combined across different experimental arms.
4 weeks
Article-reported result excerpt (24 words maximum): “However, the difference compared to before hydrogen inhalation was not statistically significant ( P > 0.05).” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
Human evidence; design, sample size and comparator limit interpretation. No funding statement was identified in the machine-readable full article; absence is not inferred. The article declares no conflicts of interest.
What kind of evidence is this?
Human
Human interventional or observational study
Other neurological conditions
Inhaled H₂
Information not yet classified
Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.
Methods
Human participants studied for other neurological conditions. See eligibility criteria in the linked full text.
Human study; the full text reports 17 patients.
4 weeks
Full text reports inhaled H₂-containing gas. Detected intervention quantities or schedules: 4 weeks, 2.0 L/min, 1.0 L/min, 3 days, 12 weeks, 8 weeks.
Inhaled molecular H₂; not classified as Brown’s gas without an H₂/O₂ composition.
H₂-related quantities reported in the intervention passages: 4 weeks, 2.0 L/min, 1.0 L/min, 3 days, 12 weeks, 8 weeks. Values are not combined across different experimental arms.
2000 mL/min H₂ reported directly in the full text.
O₂ concentration and absolute O₂ flow were not both reported in the full article; no value is inferred.
Control or comparison condition reported in the full article; see the linked methods for arm-specific details.
Outcomes and reported result
survival or mortality, clinical symptoms or functional scores, tumor growth or cancer markers, inflammation and cytokines, oxidative-stress and antioxidant markers, apoptosis or cell injury
Article-reported result excerpt (24 words maximum): “However, the difference compared to before hydrogen inhalation was not statistically significant ( P > 0.05).” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.
A reported association, difference or mechanism is not automatically a clinical benefit.
Limitations and applicability
Human evidence; design, sample size and comparator limit interpretation. No funding statement was identified in the machine-readable full article; absence is not inferred. The article declares no conflicts of interest.
Applies only to the population and protocol reported in this other neurological conditions article.
No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.
Sources and record status
PMID: 35433731 · DOI: 10.3389/fmed.2022.828370
A free full article is available through PubMed Central.
Official PubMed/PMC full article; source identity, intervention data and declarations re-audited 25 August 2026.
25 August 2026
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