Source-linked study record

Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy

Liu B, Bao Y, Ma J, Wang X, Feng Y. · Advances in radiation oncology. 2025;10(11):101879.

HumanInhaled H₂Published 2025Source checked

Study record, not medical adviceThis record reports what the source states. It is not medical advice and does not establish that molecular hydrogen is effective, safe or appropriate for any person.

Quick summary

Study at a glance

Evidence type

Human

Population or model

Human participants studied for cancer research. See eligibility criteria in the linked full text.

Intervention and dose

Full text reports inhaled H₂-containing gas. Detected intervention quantities or schedules: 66.6%, 33.3%, 2 hours, 3 L/min. · H₂-related quantities reported in the intervention passages: 66.6%, 33.3%, 2 hours, 3 L/min. Values are not combined across different experimental arms.

Duration

2 hours

Reported result

Article-reported result excerpt (24 words maximum): “The overall trend analysis confirmed a significant group effect ( P < .0001), demonstrating that hydrogen inhalation suppressed radiation-induced upregulation of IL-6 levels and…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.

Main limitation

Human evidence; design, sample size and comparator limit interpretation. Funding or grant information is reported in the full article. The article declares no conflicts of interest.

Evidence and classification

What kind of evidence is this?

Evidence type

Human

Reported design

Prospective human study

Research topic

Cancer research

Administration form

Inhaled H₂

Information not yet classified

Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.

Reported in the source

Methods

Population or model

Human participants studied for cancer research. See eligibility criteria in the linked full text.

Sample

Human study; the full text reports 66 patients, with group/assay counts including n=28, n=30.

Duration

2 hours

Intervention

Full text reports inhaled H₂-containing gas. Detected intervention quantities or schedules: 66.6%, 33.3%, 2 hours, 3 L/min.

Hydrogen form

Brown’s gas / oxyhydrogen — H₂ and O₂ co-delivered, not H₂ alone.

Dose or H₂ specification

H₂-related quantities reported in the intervention passages: 66.6%, 33.3%, 2 hours, 3 L/min. Values are not combined across different experimental arms.

H₂ flow

1998 mL/min H₂, calculated from 66.6% H₂ and 3000 mL/min total flow reported in the full text.

O₂ delivered with H₂

33.3% O₂; 999 mL/min O₂ calculated from the reported total flow.

Comparator

Control or comparison condition reported in the full article; see the linked methods for arm-specific details.

Reported, not endorsed

Outcomes and reported result

Outcomes measured

survival or mortality, clinical symptoms or functional scores, tumor growth or cancer markers, inflammation and cytokines, oxidative-stress and antioxidant markers, apoptosis or cell injury

Reported result

Extraction completeness

The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.

A reported association, difference or mechanism is not automatically a clinical benefit.

Interpretation limits

Limitations and applicability

Main methodological cautions

Human evidence; design, sample size and comparator limit interpretation. Funding or grant information is reported in the full article. The article declares no conflicts of interest.

Applies directly to

Applies only to the population and protocol reported in this cancer research article.

No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.

Sources and status

Sources and record status

Identifiers

PMID: 41020280 · DOI: 10.1016/j.adro.2025.101879

Publisher access

A free full article is available through PubMed Central.

Extraction basis

Official PubMed/PMC full article; source identity, intervention data and declarations re-audited 25 August 2026.

Last reviewed

25 August 2026

Original source ↗Lawful free full text ↗

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