Hydrogenology
Hydrogenology editorial study record

Electrolytically generated hydrogen warm water cleanses the keratin-plug-clogged hair-pores and promotes the capillary blood-streams, more markedly than normal warm water does.

Tanaka Y, Saitoh Y, Miwa N. · 2018.

HumanOther formsPublished 2018
Study record, not medical adviceThis page reports one source and Hydrogenology’s source-text extraction. It does not establish that molecular hydrogen is effective, safe or appropriate for any person. Human, animal and laboratory evidence must not be treated as equivalent.
Source and classification

What kind of evidence is this?

Evidence stream

Human

Reported design

Small uncontrolled within-person physiological study

Research topic

Skin, wound and aging research

Administration classification

Other forms

Study result signal

Exploratory positive surrogate signal.

Outcome type

Short-term physiological and cosmetic surrogate outcomes.

Reported in the source

Methods at a glance

Population or model

Healthy adult volunteers using hydrogen-rich warm water.

Sample

Small volunteer sample; outcome-specific participant counts are reported in the article.

Duration

Acute hand immersion and a seven-day bathing assessment.

Intervention

Hand immersion or bathing in electrolytically generated hydrogen-rich warm water.

Hydrogen form

H₂ dissolved in warm bath water.

H₂ specification

Water was maintained around 40°C; dissolved-H₂ conditions were measured under the article protocol.

H₂ flow

Not applicable.

O₂ delivered with H₂

No oxygen was co-delivered.

Comparator

Normal warm water and pre-exposure measurements.

Reported, not endorsed

Outcomes and reported result

Outcomes measured

Fingertip capillary flow, skin moisture and microscopy of keratin plugs.

Reported result

The article reports higher capillary-flow, skin-moisture and pore-cleansing measures after hydrogen warm water than normal warm water at selected observations.

Results-extraction completeness

The full article was checked for methods, intervention details, outcomes, positive and null findings, funding and conflicts. This record does not imply medical efficacy.

A reported association, difference or mechanism is not automatically a clinical benefit. Null findings, outcome type, study design and precision all matter.

Interpretation limits

Cautions and applicability

Design and reporting cautions

Small uncontrolled or incompletely randomized study with cosmetic surrogates and possible temperature or electrolysis-property confounding.

Applies directly to

Healthy volunteers under the reported bathing conditions only.

Preliminary appraisal framework

ROBINS-I — preliminary

Preliminary risk-of-bias status

Serious concerns

Appraisal rationale

Small sample, unclear allocation/blinding and multiple image-derived surrogate outcomes create serious concerns.

Appraisal domains

Selection and allocation checked · Confounding and co-interventions remain possible · Missing observations checked where reported · Outcome measurement varies by endpoint · Selective reporting cannot be excluded

No single-study GRADE certainty rating is assigned. Certainty is assessed by important outcome across a complete eligible evidence set, not by attaching a final grade to one source.

Provenance

Sources and record status

Identifiers

PMID: 29770191 · DOI: 10.4103/2045-9912.229598

Publisher access

A free full article is available through PubMed Central.

Extraction basis

Official PubMed Central full article and PubMed bibliographic record; source identity, methods, intervention, results, funding and conflicts checked 10 August 2026.

Record revision

2026-08-10