Hydrogenology
Source-linked study record

Effects of hydrogen-rich water bath on visceral fat and skin blotch, with boiling-resistant hydrogen bubbles

Asada R, Saitoh Y, Miwa N. · Medical Gas Research. 2019;9(2):68–73.

HumanOther formsPublished 2019Source checked
Study record, not medical adviceThis record reports what the source states. It is not medical advice and does not establish that molecular hydrogen is effective, safe or appropriate for any person.
Quick summary

Study at a glance

Evidence type

Human

Population or model

Two men and two women aged 41–48 years, each assigned different skin, waist/visceral-fat or blood-marker observations.

Intervention and dose

Immersion in 40–41 °C H₂-rich bath/washbowl water for 10–15 minutes per session over one to seven months, with schedules differing by participant. · Bath/washbowl dissolved H₂ was generally reported as 175–300 μg/L (normal water <10 μg/L); the large bath contained 180–200 L. Water tests examined retention after boiling.

Duration

One to seven months depending on outcome; most full-body sessions were 10 minutes daily.

Reported result

The report describes lighter/smaller photographed blotches and lower waist/visceral-fat measurements in selected participants; one participant's LDL changed from 132 to 109 mg/dL and fasting glucose from 103 to 89 mg/dL at six months. The abstract incorrectly says fasting glucose increased 13.6%, whereas its own table shows a decrease of that magnitude. No inferential clinical statistics or controlled comparison were provided.

Main limitation

Only four uncontrolled cases with different regimens/outcomes, subjective photographs, no sham/temperature control, lifestyle self-report, commercial bath apparatus, mechanistic speculation and an internal glucose-reporting contradiction. A Japanese anti-aging NPO grant partly supported the work; authors declared no conflicts.

Evidence and classification

What kind of evidence is this?

Evidence type

Human

Reported design

Uncontrolled four-person collection of heterogeneous before/after bathing case observations plus water-characterization tests

Research topic

Skin, wound and aging research

Administration form

Other forms

Information not yet classified

Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.

Reported in the source

Methods

Population or model

Two men and two women aged 41–48 years, each assigned different skin, waist/visceral-fat or blood-marker observations.

Sample

Four participants total; individual outcomes were usually reported for one to three participants, without a concurrent control group.

Duration

One to seven months depending on outcome; most full-body sessions were 10 minutes daily.

Intervention

Immersion in 40–41 °C H₂-rich bath/washbowl water for 10–15 minutes per session over one to seven months, with schedules differing by participant.

Hydrogen form

H₂ dissolved in bath water generated electrolytically — not classified as Brown's gas because the study did not report an H₂/O₂ gas composition, and not inhalation.

Dose or H₂ specification

Bath/washbowl dissolved H₂ was generally reported as 175–300 μg/L (normal water <10 μg/L); the large bath contained 180–200 L. Water tests examined retention after boiling.

Comparator

Each participant's own baseline only; no sham bath, ordinary-water control, randomization or blinding.

Reported, not endorsed

Outcomes and reported result

Outcomes measured

Photographic skin blotches/appearance, waist circumference, ultrasound-estimated visceral fat in three participants and lipid/glucose values in one participant.

Reported result

The report describes lighter/smaller photographed blotches and lower waist/visceral-fat measurements in selected participants; one participant's LDL changed from 132 to 109 mg/dL and fasting glucose from 103 to 89 mg/dL at six months. The abstract incorrectly says fasting glucose increased 13.6%, whereas its own table shows a decrease of that magnitude. No inferential clinical statistics or controlled comparison were provided.

Extraction completeness

The complete free PMC article, participant-specific protocols, photographs/tables, water tests and disclosures were checked for dissolved concentration, missing flow/composition, heterogeneous outcomes, the abstract/table glucose contradiction, funding and conflicts.

A reported association, difference or mechanism is not automatically a clinical benefit.

Interpretation limits

Limitations and applicability

Main methodological cautions

Only four uncontrolled cases with different regimens/outcomes, subjective photographs, no sham/temperature control, lifestyle self-report, commercial bath apparatus, mechanistic speculation and an internal glucose-reporting contradiction. A Japanese anti-aging NPO grant partly supported the work; authors declared no conflicts.

Applies directly to

Very low-certainty cosmetic/metabolic observations; they do not establish that H₂ bathing changes skin disease, body fat, cholesterol or glucose.

No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.

Sources and status

Sources and record status

Identifiers

PMID: 31249254 · DOI: 10.4103/2045-9912.260647

Publisher access

Free full article in PubMed Central.

Extraction basis

Complete PMC article and PubMed metadata; full-text extraction checked 9 August 2026.

Last reviewed

10 August 2026

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