Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats
Liu B, Xue J, Zhang M, Wang M, Ma T, Zhao M, Gu Q, Qin S. · Molecular medicine reports. 2020;22(4):2860-2868.
Molecular hydrogen (H2) and Metabolic and lipid health
Browse 72 source-checked metabolic and lipid health records involving molecular hydrogen (H2), with human and preclinical evidence clearly separated.
72full-text-checked records
18human studies
54animal and laboratory records
No treatment conclusion is impliedGlucose regulation, lipid measures, clinical outcomes and safety are not treated as interchangeable. Every result must be interpreted in the context of its design, population or model, intervention, comparator and measured outcome.
iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment
Jiang Y, Bian Y, Lian N, Wang Y, Xie K, Qin C, Yu Y. · Drug design, development and therapy. 2020;14:4885-4900.
MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline
Yao W, Lin X, Han X, Zeng L, Guo A, Guan Y, Hei Z, Liu J, Huang P. · Bioscience reports. 2020;40(1):BSR20191043.
Molecular hydrogen improves type 2 diabetes through inhibiting oxidative stress
Ming Y, Ma QH, Han XL, Li HY. · Experimental and therapeutic medicine. 2020;20(1):359-366.
Protective effects of hydrogen-rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP-sensitive potassium channel channels in rats
Jiao Y, Yu Y, Li B, Gu X, Xie K, Wang G, Yu Y. · Molecular medicine reports. 2020;21(1):282-290.
The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial
LeBaron TW et al. · Diabetes Metab Syndr Obes. 2020;13:889–896.
Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment
Wen D, Hui R, Wang J, Shen X, Xie B, Gong M, Yu F, Cong B, Ma C. · Frontiers in pharmacology. 2019;10:823.
Hydrogen-rich medium alleviates high glucose-induced oxidative stress and parthanatos in rat Schwann cells in vitro
Li Q, Jiao Y, Yu Y, Wang G, Yu Y. · Molecular Medicine Reports. 2019;19(1):338–344.
Intake of Molecular Hydrogen in Drinking Water Increases Membrane Transporters, p -Glycoprotein, and Multidrug Resistance-Associated Protein 2 without Affecting Xenobiotic-Metabolizing Enzymes in Rat Liver
Yao HT, Yang YH, Li ML. · Molecules (Basel, Switzerland). 2019;24(14):E2627.
Protein chip and bioinformatic analyses of differentially expressed proteins involved in the effect of hydrogen-rich water on myocardial ischemia-reperfusion injury
Li L, Liu T, Li X, Liu X, Liu L, Li S, Li Z, Zhou Y, Liu F. · International journal of medical sciences. 2019;16(9):1254-1259.
Effects of alkaline-electrolyzed and hydrogen-rich water, in a high-fat-diet nonalcoholic fatty liver disease mouse model
Jackson K, Dressler N, Ben-Shushan RS, Meerson A, LeBaron TW, Tamir S. · World journal of gastroenterology. 2018;24(45):5095-5108.
Subcutaneous injection of hydrogen gas is a novel effective treatment for type 2 diabetes
Zhang X, Liu J, Jin K, Xu H, Wang C, Zhang Z, Kong M, Zhang Z, Wang Q, Wang F. · Journal of diabetes investigation. 2018;9(1):83-90.
Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice
Lin CP, Chuang WC, Lu FJ, Chen CY. · World journal of gastroenterology. 2017;23(27):4920-4934.
Dissolved molecular hydrogen (H_2) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity
Nakayama M, Zhu WJ, Watanabe K, Gibo A, Sherif AM, Kabayama S, Ito S. · BMC nephrology. 2017;18(1):327.
Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis
Li J, Ge Z, Fan L, Wang K. · BMC musculoskeletal disorders. 2017;18(1):58.
Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism
Kamimura N, Ichimiya H, Iuchi K, Ohta S. · NPJ Aging and Mechanisms of Disease. 2016;2:16008.
Cigarette smoke exposure impairs reverse cholesterol transport which can be minimized by treatment of hydrogen-saturated saline
Zong C, Song G, Yao S, Guo S, Yu Y, Yang N, Guo Z, Qin S. · Lipids in health and disease. 2015;14:159.
Hydrogen-Rich Saline Attenuates Acute Renal Injury in Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting ROS and NF- κ B Pathway
Shi Q, Liao KS, Zhao KL, Wang WX, Zuo T, Deng WH, Chen C, Yu J, Guo WY, He XB, Abliz A, Wang P, Zhao L. · Mediators of inflammation. 2015;2015:685043.
Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome
Song G et al. · J Lipid Res. 2013;54(7):1884–1893.
Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells
Iio A, Ito M, Itoh T, Terazawa R, Fujita Y, Nozawa Y, Ohsawa I, Ohno K, Ito M. · Medical gas research. 2013;3(1):6.
Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg- Lepr ^ cp /NDmcr rat kidney
Katakura M, Hashimoto M, Tanabe Y, Shido O. · Medical gas research. 2012;2(1):18.
Effects of hydrogen-rich water on abnormalities in a SHR.Cg- Lepr^cp /NDmcr rat - a metabolic syndrome rat model
Hashimoto M, Katakura M, Nabika T, Tanabe Y, Hossain S, Tsuchikura S, Shido O. · Medical gas research. 2011;1(1):26.
Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus.
Li Y, Hamasaki T, Nakamichi N, Kashiwagi T, Komatsu T, Ye J, Teruya K, Abe M, Yan H, Kinjo T, Kabayama S, Kawamura M, Shirahata S. · Cytotechnology. 2011;63:119-131.
Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome—an open label pilot study
Nakao A et al. · J Clin Biochem Nutr. 2010;46(2):140–149.