Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats
Han XC, Ye ZH, Hu HJ, Sun Q, Fan DF. · Medical Gas Research. 2023;13(2):72–77.
Molecular hydrogen (H2) and Metabolic and lipid health
Browse 72 source-checked metabolic and lipid health records involving molecular hydrogen (H2), with human and preclinical evidence clearly separated.
72full-text-checked records
18human studies
54animal and laboratory records
No treatment conclusion is impliedGlucose regulation, lipid measures, clinical outcomes and safety are not treated as interchangeable. Every result must be interpreted in the context of its design, population or model, intervention, comparator and measured outcome.
Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study
Liang B et al. · Antioxidants (Basel). 2023;12(6):1245.
Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF-κB Inflammatory Pathway
Yang WC, Li TT, Wan Q, Zhang X, Sun LY, Zhang YR, Lai PC, Li WZ. · Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023;18(1-2):90-99.
Molecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans
Korovljev D, Ostojic J, Todorovic N, Ostojic SM. · Archives of medical science : AMS. 2023;19(4):1151-1153.
Real-World Effectiveness and Safety of Hydrogen Inhalation in Chinese Patients with Type 2 Diabetes: A Single-Arm, Retrospective Study
Ji H, Zhao Z, Liu Z, Sun R, Li Y, Ding X, Ni T. · Diabetes, metabolic syndrome and obesity : targets and therapy. 2023;16:2039-2050.
The Effect of Molecular Hydrogen on Functional States of Erythrocytes in Rats with Simulated Chronic Heart Failure
Deryugina AV, Danilova DA, Pichugin VV, Brichkin YD. · Life (Basel, Switzerland). 2023;13(2):418.
Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage
Ma L, Tian S, Zhang HL, Wang JY, Wang JW, Yan HL, Hu XG, Shao Q, Guo JM. · Frontiers in public health. 2023;11:1103022.
Antioxidant effects of continuous intake of electrolyzed hydrogen water in healthy adults
Mizuno K, Watanabe K, Yamano E, Ebisu K, Tajima K, Nojima J, Ohsaki Y, Kabayama S, Watanabe Y. · Heliyon. 2022;8(11):e11853.
Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status
Xie F, Jiang X, Yi Y, Liu ZJ, Ma C, He J, Xun ZM, Wang M, Liu MY, Mawulikplimi Adzavon Y, Zhao PX, Ma XM. · Scientific reports. 2022;12(1):7231.
Effectiveness and safety of hydrogen inhalation as an adjunct treatment in Chinese type 2 diabetes patients: A retrospective, observational, double-arm, real-life clinical study
Zhao Z, Ji H, Zhao Y, Liu Z, Sun R, Li Y, Ni T. · Frontiers in endocrinology. 2022;13:1114221.
Efficacy and safety of hydrogen inhalation therapy in type 2 diabetes mellitus patients inadequately controlled by metformin alone
Lin G, Ni T. · Adv Clin Med. 2022;12(10):9605–9612.
Electrolyzed hydrogen-rich water for oxidative stress suppression and improvement of insulin resistance: a multicenter prospective double-blind randomized control trial
Ogawa S, Ohsaki Y, Shimizu M, et al. · Diabetology International. 2022;13(1):209–219.
Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway
Li Y, Shen C, Zhou X, Zhang J, Lai X, Zhang Y. · Oxidative medicine and cellular longevity. 2022;2022:2949824.
Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways
Adzavon YM, Xie F, Yi Y, Jiang X, Zhang X, He J, Zhao P, Liu M, Ma S, Ma X. · Scientific reports. 2022;12(1):3904.
Molecular Hydrogen Reduces Electromagnetic Pulse-Induced Male Rat Reproductive System Damage in a Rodent Model
Ma L, Hao W, Feng WB, Cao LC, Qin LN, Wang Y, Liu MH, Wang NZ, Gao F, Guo JM, Du H, Yan HL. · Oxidative medicine and cellular longevity. 2022;2022:3469474.
The improvement of insulin level after hydrogen-rich water therapy in streptozotocin-induced diabetic rats
Retnaningtyas E, Susatia B, Arifah SN, Rahayu Lestari S. · Veterinary world. 2022;15(1):182-187.
A Preliminary Study on the Effect of Hydrogen Gas on Alleviating Early CCl_4-Induced Chronic Liver Injury in Rats
Wang J, Cheng Q, Fang J, Ding H, Liu H, Fang X, Chen C, Zhang W. · Antioxidants (Basel, Switzerland). 2021;10(12):1933.
Drinking Molecular Hydrogen Water Is Beneficial to Cardiovascular Function in Diet-Induced Obesity Mice
Masuda H, Sato A, Miyata K, Shizuno T, Oyamada A, Ishiwata K, Nakagawa Y, Asahara T. · Biology. 2021;10(5):364.
Hydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation
Zhang Y, Bi M, Chen Z, Dai M, Zhou G, Hu Y, Yang H, Guan W. · Experimental and therapeutic medicine. 2021;21(5):453.
Hydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo
Li H, Yin Y, Liu J, Lu B, Wan H, Yang L, Wang W, Li R. · Journal of radiation research. 2021;62(1):34-45.
Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs
Ichihara G, Katsumata Y, Moriyama H, Kitakata H, Hirai A, Momoi M, Ko S, Shinya Y, Kinouchi K, Kobayashi E, Sano M. · Heliyon. 2021;7(11):e08359.
Protective Effect of Molecular Hydrogen Following Different Routes of Administration on D-Galactose-Induced Aging Mice
Liu B, Xie Y, Chen J, Xue J, Zhang X, Zhao M, Jia X, Wang Y, Qin S. · Journal of inflammation research. 2021;14:5541-5550.
Effects of hydrogen-rich water prepared by alternating-current-electrolysis on antioxidant activity, DNA oxidative injuries, and diabetes-related markers
Asada R, Tazawa K, Sato S, Miwa N. · Medical Gas Research. 2020;10(3):114–121.
Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats
Wang P, Zhao M, Chen Z, Wu G, Fujino M, Zhang C, Zhou W, Zhao M, Hirano SI, Li XK, Zhao L. · Oxidative medicine and cellular longevity. 2020;2020:6978784.