Molecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans
Korovljev D, Ostojic J, Todorovic N, Ostojic SM. · Archives of medical science : AMS. 2023;19(4):1151-1153.
Study at a glance
Human
Human participants studied for metabolic and lipid health. See eligibility criteria in the linked full text.
Full text reports H₂ dissolved in drinking water. Detected intervention quantities or schedules: 12 weeks. · H₂-related quantities reported in the intervention passages: 12 weeks. Values are not combined across different experimental arms.
12 weeks
Article-reported result excerpt (24 words maximum): “Other metabolites were not affected by hydrogen intervention ( p > 0.05), except for a significant rise in brain taurine levels in the posterior…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
Human evidence; design, sample size and comparator limit interpretation. No funding statement was identified in the machine-readable full article; absence is not inferred. The article declares no conflicts of interest.
What kind of evidence is this?
Human
Human interventional or observational study
Metabolic and lipid health
H₂-rich water
Information not yet classified
Some editorial classification fields are still pending. The source-reported outcomes and result are shown below; Hydrogenology does not infer a positive or negative signal from prose automatically.
Methods
Human participants studied for metabolic and lipid health. See eligibility criteria in the linked full text.
Human study; group or assay counts reported in the full text include n=4.
12 weeks
Full text reports H₂ dissolved in drinking water. Detected intervention quantities or schedules: 12 weeks.
H₂ dissolved in drinking water — H₂ only unless the full text explicitly reports oxygen co-delivery.
H₂-related quantities reported in the intervention passages: 12 weeks. Values are not combined across different experimental arms.
Control or comparison condition reported in the full article; see the linked methods for arm-specific details.
Outcomes and reported result
survival or mortality, clinical symptoms or functional scores, oxidative-stress and antioxidant markers, apoptosis or cell injury, metabolic laboratory measures
Article-reported result excerpt (24 words maximum): “Other metabolites were not affected by hydrogen intervention ( p > 0.05), except for a significant rise in brain taurine levels in the posterior…” This excerpt is not a complete result summary; consult the linked full text for all positive and null findings.
The complete machine-readable article was checked for source identity, methods, intervention quantities, results, tables, funding and conflict declarations. This public record is based on the full article.
A reported association, difference or mechanism is not automatically a clinical benefit.
Limitations and applicability
Human evidence; design, sample size and comparator limit interpretation. No funding statement was identified in the machine-readable full article; absence is not inferred. The article declares no conflicts of interest.
Applies only to the population and protocol reported in this metabolic and lipid health article.
No single-study GRADE certainty rating is assigned. Read how records and evidence assessments are prepared.
Sources and record status
PMID: 37560746 · DOI: 10.5114/aoms/162938
A free full article is available through PubMed Central.
Official PubMed/PMC full article; source identity, intervention data and declarations re-audited 25 August 2026.
25 August 2026
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