Hydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB Signaling Pathway
Fu Z, Zhang Z, Wu X, Zhang J. · BioMed research international. 2020;2020:9121894.
Other molecular hydrogen forms research
Browse 261 source-checked molecular hydrogen records classified as other forms, with human and preclinical evidence separated.
261full-text-checked records
57human studies
204animal and laboratory records
No treatment conclusion is impliedAdministration routes, concentrations, doses and treatment schedules vary and must not be treated as interchangeable. Every result must be interpreted in the context of its design, population or model, intervention, comparator and measured outcome.
Hydrogen-rich saline mitigates pressure-overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway
Wang C, Pan Z. · J Int Med Res. 2020;48(8):300060520936415.
Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway
Ke H, Liu D, Li T, Chu X, Xin D, Han M, Wang S, Wang Z. · Drug design, development and therapy. 2020;14:3827-3839.
iTRAQ-Based Quantitative Proteomic Analysis of Intestines in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment
Jiang Y, Bian Y, Lian N, Wang Y, Xie K, Qin C, Yu Y. · Drug design, development and therapy. 2020;14:4885-4900.
MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline
Yao W, Lin X, Han X, Zeng L, Guo A, Guan Y, Hei Z, Liu J, Huang P. · Bioscience reports. 2020;40(1):BSR20191043.
Molecular hydrogen improves type 2 diabetes through inhibiting oxidative stress
Ming Y, Ma QH, Han XL, Li HY. · Experimental and therapeutic medicine. 2020;20(1):359-366.
Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method.
Kawamura M, Imamura R, Kobayashi Y, Taniguchi A, Nakazawa S, Kato T, Namba-Hamano T, Abe T, Uemura M, Kobayashi H, Nonomura N. · 2020.
Protective effects of hydrogen-rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP-sensitive potassium channel channels in rats
Jiao Y, Yu Y, Li B, Gu X, Xie K, Wang G, Yu Y. · Molecular medicine reports. 2020;21(1):282-290.
Suppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis
Liu L, Yan Z, Wang Y, Meng J, Chen G. · Oncology letters. 2020;20(4):112.
Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. Randomized, Double-Blinded, Placebo-Controlled Crossover Pilot Study
LeBaron TW, Larson AJ, Ohta S, Mikami T, Barlow J, Bulloch J, DeBeliso M. · Journal of lifestyle medicine. 2019;9(1):36-43.
Case Report: Buccal administration of hydrogen-producing blend after a mild traumatic brain injury in a professional athlete
Javorac D, Stajer V, Ostojic SM. · 2019.
Effect of H_2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease
Terasaki Y, Terasaki M, Kanazawa S, Kokuho N, Urushiyama H, Kajimoto Y, Kunugi S, Maruyama M, Akimoto T, Miura Y, Igarashi T, Ohsawa I, Shimizu A. · Journal of cellular and molecular medicine. 2019;23(10):7043-7053.
Effects of Hydrogen in Prevention of Corneal Endothelial Damage During Phacoemulsification: A Prospective Randomized Clinical Trial
Igarashi T et al. · Am J Ophthalmol. 2019;207:10–17.
Effects of hydrogen-rich water bath on visceral fat and skin blotch, with boiling-resistant hydrogen bubbles
Asada R, Saitoh Y, Miwa N. · Medical Gas Research. 2019;9(2):68–73.
Hydrogen-rich medium alleviates high glucose-induced oxidative stress and parthanatos in rat Schwann cells in vitro
Li Q, Jiao Y, Yu Y, Wang G, Yu Y. · Molecular Medicine Reports. 2019;19(1):338–344.
Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial ischemia-reperfusion injury via PINK-mediated autophagy
Yao L et al. · Int J Mol Med. 2019;44(3):1048–1062.
Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice
Wang Y, Zhang J, Bo J, Wang X, Zhu J. · Experimental Biology and Medicine. 2019;244(9):721-727.
Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic injury in neonatal mice via AMPK activation
Chu X et al. · J Neuroinflammation. 2019;16:104.
Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction
Iuchi K, Nishimaki K, Kamimura N, Ohta S. · Can J Physiol Pharmacol. 2019;97(10):999–1005.
Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs
Kobayashi E, Sano M. · PloS one. 2019;14(10):e0222863.
Perioperatively inhaled hydrogen gas diminishes neurologic injury following experimental circulatory arrest in swine
Cole AR et al. · JACC Basic Transl Sci. 2019;4(2):176–187.
Protective effects of hydrogen-rich saline against renal ischemia-reperfusion injury by increased expression of heme oxygenase-1 in aged rats
Xu X, He X, Liu J, Qin J, Ye J, Fan M. · International Journal of Clinical and Experimental Pathology. 2019;12(4):1488-1496.
Protective Role of Hydrogen Gas on Oxidative Damage and Apoptosis in Intestinal Porcine Epithelial Cells (IPEC-J2) Induced by Deoxynivalenol: A Preliminary Study
Ji X, Zheng W, Yao W. · Toxins. 2019;12(1):E5.
Electrolytically generated hydrogen warm water cleanses the keratin-plug-clogged hair-pores and promotes the capillary blood-streams, more markedly than normal warm water does.
Tanaka Y, Saitoh Y, Miwa N. · 2018.