Hydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells
Zhang B, Zhao Z, Meng X, Chen H, Fu G, Xie K. · Int J Mol Med. 2018;41(6):3653–3661.
Other molecular hydrogen forms research
Browse 261 source-checked molecular hydrogen records classified as other forms, with human and preclinical evidence separated.
261full-text-checked records
57human studies
204animal and laboratory records
No treatment conclusion is impliedAdministration routes, concentrations, doses and treatment schedules vary and must not be treated as interchangeable. Every result must be interpreted in the context of its design, population or model, intervention, comparator and measured outcome.
Hydrogen Flush After Cold Storage as a New End‐Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury
Tamaki I, Hata K, Okamura Y, Nigmet Y, Hirao H, Kubota T, Inamoto O, Kusakabe J, Goto T, Tajima T, Yoshikawa J, Tanaka H, Tsuruyama T, Tolba RH, Uemoto S. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2018;24(11):1589-1602.
Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the JAK2/STAT3 signaling pathway
Chen K, Sun Y, Diao Y, Zhang T, Dong W. · Oncology Letters. 2018;16(1):167–178.
Influence of Hydrogen-rich Saline on Hepatocyte Autophagy During Laparoscopic Liver Ischaemia-reperfusion Combined Resection Injury in Miniature Pigs
Bai G, Li H, Ge Y, Zhang Q, Zhang J, Chen M, Liu T, Wang H. · Journal of veterinary research. 2018;62(3):395-403.
Involvement of Neutrophil Dynamics and Function in Exercise-Induced Muscle Damage and Delayed-Onset Muscle Soreness: Effect of Hydrogen Bath
Kawamura T, Suzuki K, Takahashi M, Tomari M, Hara R, Gando Y, Muraoka I. · Antioxidants. 2018;7(10):127.
Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen
Franceschelli S et al. · J Cell Mol Med. 2018;22(5):2750–2759.
Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty-liver model via regulating HO-1 and Sirt1 expression
Li S et al. · Sci Rep. 2018;8:14019.
Novel haemodialysis treatment employing molecular hydrogen-enriched dialysis solution improves prognosis of chronic dialysis patients: a prospective observational study
Nakayama M et al. · Sci Rep. 2018;8:254.
Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques
Zhu Q, Wu Y, Li Y, Chen Z, Wang L, Xiong H, Dai E, Wu J, Fan B, Ping L, Luo X. · Scientific Reports. 2018;8:8051.
Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling
Fan Z, Gao Y, Huang Z, Xue F, Wu S, Yang J, Zhu L, Fu L. · BMC cardiovascular disorders. 2018;18(1):32.
Protective effects of hydrogen-rich medium on lipopolysaccharide-induced injury in human periodontal ligament cells
Zhou M, Wang ZL. · West China Journal of Stomatology. 2018;36(2):123-127.
Subcutaneous injection of hydrogen gas is a novel effective treatment for type 2 diabetes
Zhang X, Liu J, Jin K, Xu H, Wang C, Zhang Z, Kong M, Zhang Z, Wang Q, Wang F. · Journal of diabetes investigation. 2018;9(1):83-90.
Therapeutic efficacy of hydrogen-rich saline alone and in combination with PI3K inhibitor in non-small cell lung cancer
Jiang Y et al. · Mol Med Rep. 2018;18(2):2182-2190.
Dissolved molecular hydrogen (H_2) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity
Nakayama M, Zhu WJ, Watanabe K, Gibo A, Sherif AM, Kabayama S, Ito S. · BMC nephrology. 2017;18(1):327.
Effect of Hydrogen-Rich Saline on Postoperative Intra-Abdominal Adhesion Bands Formation in Mice
Liu Z, Cheng S, Gu C, Pei H, Hong X. · Medical science monitor : international medical journal of experimental and clinical research. 2017;23:5363-5373.
Effects of hydrogen-rich saline on endotoxin-induced uveitis
Yan WM, Zhang L, Chen T, Zhao GH, Long P, An J, Zhang ZM. · Medical Gas Research. 2017;7(1):9–18.
Hydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells
Yu J, Yu Q, Liu Y, Zhang R, Xue L. · PLOS ONE. 2017;12(3):e0173645.
Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress
Wu CY, Hsu WL, Tsai MH, Liang JL, Lu JH, Yen CJ, Yu HS, Noda M, Lu CY, Chen CH, Yan SJ, Yoshioka T. · Scientific Reports. 2017;7:3606.
Hydrogen treatment protects against cell death and senescence induced by oxidative damage
Han AL, Park SH, Park MS. · J Microbiol Biotechnol. 2017;27(2):365–371.
Hydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats.
Yang J, Wu S, Zhu L, Cai J, Fu L. · Molecular Medicine Reports. 2017;16:6849.
Hydrogen-rich saline alleviates kidney fibrosis following acute kidney injury and retains Klotho expression
Chen J et al. · Front Pharmacol. 2017;8:499.
Hydrogen-rich saline attenuates brain injury induced by cardiopulmonary bypass and inhibits microvascular endothelial cell apoptosis via the PI3K/Akt/GSK3β signaling pathway in rats
Chen K et al. · Cell Physiol Biochem. 2017;43(4):1634–1647.
Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress
Yu S, Zhao C, Che N, Jing L, Ge R. · Journal of inflammation (London, England). 2017;14:1.
Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels
Li C, Hou L, Chen D, Lin F, Chang T, Li M, Zhang L, Niu X, Wang H, Fu S, Zheng J. · American Journal of Translational Research. 2017;9(3):1162-1172.