Hydrogen-Rich Gas Enhanced Sprint-Interval Performance: Metabolomic Insights into Underlying Mechanisms
Dong G, Liu H, Chen Y, Bao D, Xu W, Zhou J. · Nutrients. 2024;16(14):2341.
Inhaled molecular hydrogen research
Inhaled molecular hydrogen research: 185 source-checked studies (63 human; 122 preclinical). Compare delivery, outcomes and limitations.
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No treatment conclusion is impliedH₂ concentration, gas mixture, delivery system, flow, duration and treatment schedules vary and must not be treated as interchangeable. Every result must be interpreted in the context of its design, population or model, intervention, comparator and measured outcome.
Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy
Cui Y, Li Y, Meng S, Song Y, Xie K. · BMC anesthesiology. 2024;24(1):72.
Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice
Guo Y, Qin J, Sun R, Hao P, Jiang Z, Wang Y, Gao Z, Zhang H, Xie K, Zhang W. · Biological research. 2024;57(1):43.
Pilot Feasibility and Safety Study of Hydrogen Gas Inhalation in Locally Advanced Head and Neck Cancer Patients
Chitapanarux I, Onchan W, Chakrabandhu S, Muangwong P, Autsavapromporn N, Ariyanon T, Akagi J, Mizoo A. · OncoTargets and therapy. 2024;17:863-870.
Successful treatment of myalgic encephalomyelitis/chronic fatigue syndrome using hydrogen gas: four case reports
Hirano SI, Ichikawa Y, Sato B, Takefuji Y, Satoh F. · Medical Gas Research. 2024;14(2):84–86.
The Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension
Atiakshin D, Kostin A, Alekhnovich A, Volodkin A, Ignatyuk M, Klabukov I, Baranovskii D, Buchwalow I, Tiemann M, Artemieva M, Medvedeva N, LeBaron TW, Noda M, Medvedev O. · International journal of molecular sciences. 2024;25(20):11010.
A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases
Tao G, Liu F, Jin Z, Liu B, Wang H, Li D, Tang W, Chen Y, He Q, Qin S. · Theranostics. 2023;13(8):2455-2470.
APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis
Wang Y, Fan Y, Jiang Y, Wang E, Song Y, Chen H, Xu F, Xie K, Yu Y. · International journal of molecular sciences. 2023;24(14):11325.
Conflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model
Htun Y, Nakamura S, Nakao Y, Mitsuie T, Ohta K, Arioka M, Yokota T, Inoue E, Inoue K, Tsuchiya T, Koyano K, Konishi Y, Miki T, Ueno M, Kusaka T. · Scientific Reports. 2023;13:10486.
Effect of hydrogen/oxygen therapy for ordinary COVID-19 patients: a propensity-score matched case-control study
Zeng Y, Guan W, Wang K, Jie Z, Zou X, Tan X, Li X, Chen X, Ren X, Jiang J, Zheng Z, Shi J, Zhong N. · BMC Infectious Diseases. 2023;23:440.
Effect of molecular hydrogen treatment on Sepsis‐Associated encephalopathy in mice based on gut microbiota
Han Q, Bai Y, Zhou C, Dong B, Li Y, Luo N, Chen H, Yu Y. · CNS neuroscience & therapeutics. 2023;29(2):633-645.
Effect of molecular hydrogen, a novelly-established antioxidant, on the retinal degeneration of hereditary retinitis pigmentosa: an in-vivo study
Yan W, He Q, Long P, Chen T, Zhang L, Wang H. · Frontiers in pharmacology. 2023;14:1294315.
Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial
Rahman MH et al. · Antioxidants (Basel). 2023;12(6):1241.
Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia
Nascimento GC, Santos BM, Pedrazzi JF, Silva-Amaral D, Bortolanza M, Harris GT, Del Bel E, Branco LGS. · Brain, Behavior, & Immunity - Health. 2023;30:100623.
Efficacy of donepezil plus hydrogen–oxygen mixture inhalation for treatment of patients with Alzheimer disease: A retrospective study
Dan Z, Li H, Xie J. · Medicine. 2023;102(30):e34382.
High-concentration hydrogen mitigates sepsis-induced acute lung injury in mice by alleviating mitochondrial fission and dysfunction
Zhao N, Sun R, Cui Y, Song Y, Ma W, Li Y, Liang J, Wang G, Yu Y, Han J, Xie K. · J Pers Med. 2023;13(2):244.
Hydrogen Gas Inhalation Attenuates Acute Impulse Noise Trauma: A Preclinical In Vivo Study
Videhult Pierre P, Fransson A, Kisiel MA, Laurell G. · The Annals of otology, rhinology, and laryngology. 2023;132(8):865-872.
Hydrogen Inhalation Ameliorates Oxidative Stress and Glucose Metabolism Disorder in the Brain of Hindlimb Unloading Rats
Jin X, Xie F, Yi Y, Zhang Y, Ling S, Shen Q, Ma X, Li Y. · Space: Science & Technology. 2023;3:0027.
Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice
Ageta K et al. · Surgery. 2023;174(2):343-349.
Hydrogen Inhalation Reduces Lung Inflammation and Blood Pressure in the Experimental Model of Pulmonary Hypertension in Rats
Kuropatkina T, Atiakshin D, Sychev F, Artemieva M, Samoilenko T, Gerasimova O, Shishkina V, Gufranov K, Medvedeva N, LeBaron TW, Medvedev O. · Biomedicines. 2023;11(12):3141.
Impact of hydrogen gas inhalation during therapeutic hypothermia on cerebral hemodynamics and oxygenation in the asphyxiated piglet
Nakamura S, Nakao Y, Htun Y, Mitsuie T, Koyano K, Morimoto A, Konishi Y, Arioka M, Kondo S, Kato I, Ohta KI, Yasuda S, Miki T, Ueno M, Kusaka T. · Scientific reports. 2023;13(1):1615.
Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury.
Xue JL, Liu BY, Zhao M, Zhang MY, Wang MY, Gu QQ, Zhang XY, Qin SC. · 2023.
Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation
de Deus JL, Amorim MR, da Silva Junior RMP, Jesus AA, de Barcellos Filho PCG, Cárnio EC, Cunha AOS, Leão RM, Branco LGS. · Brain, behavior, & immunity - health. 2023;31:100654.
Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF-κB Inflammatory Pathway
Yang WC, Li TT, Wan Q, Zhang X, Sun LY, Zhang YR, Lai PC, Li WZ. · Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023;18(1-2):90-99.