Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression
Long P, Yan W, He M, Zhang Q, Wang Z, Li M, Xue J, Chen T, An J, Zhang Z. · BMC ophthalmology. 2019;19(1):112.
Inhaled molecular hydrogen research
Inhaled molecular hydrogen research: 185 source-checked studies (63 human; 122 preclinical). Compare delivery, outcomes and limitations.
Choose an evidence group to browse its records. Start with the molecular hydrogen research overview.
No treatment conclusion is impliedH₂ concentration, gas mixture, delivery system, flow, duration and treatment schedules vary and must not be treated as interchangeable. Every result must be interpreted in the context of its design, population or model, intervention, comparator and measured outcome.
Safety of inhaled hydrogen gas in healthy mice
Cole AR, Raza A, Ahmed H, Polizzotti BD, Padera RF, Andrews N, Kheir JN. · Medical Gas Research. 2019;9(3):133–138.
Short-term H_2 inhalation improves running performance and torso strength in healthy adults
Javorac D, Stajer V, Ratgeber L, Betlehem J, Ostojic S. · Biology of sport. 2019;36(4):333-339.
Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model
Imai K, Kotani T, Tsuda H, Nakano T, Ushida T, Iwase A, Nagai T, Toyokuni S, Suzumura A, Kikkawa F. · Scientific reports. 2018;8(1):9221.
Beneficial effects of hydrogen gas inhalation on a murine model of allergic rhinitis
Fang S, Li X, Wei X, Zhang Y, Ma Z, Wei Y, Wang W. · Experimental and therapeutic medicine. 2018;16(6):5178-5184.
Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats
Yan W, Chen T, Long P, Zhang Z, Liu Q, Wang X, An J, Zhang Z. · Medical science monitor : international medical journal of experimental and clinical research. 2018;24:3840-3847.
Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice
Lu W, Li D, Hu J, Mei H, Shu J, Long Z, Yuan L, Li D, Guan R, Li Y, Xu J, Wang T, Yao H, Zhong N, Zheng Z. · Journal of Thoracic Disease. 2018;10(6):3232–3243.
Hydrogen gas inhalation protects against cutaneous ischaemia/reperfusion injury in a mouse model of pressure ulcer
Fang W, Wang G, Tang L, Su H, Chen H, Liao W, Xu J. · Journal of cellular and molecular medicine. 2018;22(9):4243-4252.
Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis
Huang JL, Liu WW, Sun XJ. · Medical Gas Research. 2018;8(1):1–5.
Inhalation of high concentration hydrogen gas improves short-term outcomes in a rat model of asphyxia induced-cardiac arrest
Huang L, Applegate RL II, Applegate PM, Boling W, Zhang JH. · Medical Gas Research. 2018;8(3):73–78.
Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats
Chi J, Li Z, Hong X, Zhao T, Bie Y, Zhang W, Yang J, Feng Z, Yu Z, Xu Q, Zhao L, Liu W, Gao Y, Yang H, Yang J, Liu J, Yang W. · Frontiers in physiology. 2018;9:1026.
Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
Zhang N, Deng C, Zhang X, Zhang J, Bai C. · Asthma research and practice. 2018;4:3.
Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease
Hirayama M, Ito M, Minato T, Yoritaka A, LeBaron TW, Ohno K. · Medical Gas Research. 2018;8(4):144–149.
Molecular hydrogen alleviates asphyxia-induced neuronal cyclooxygenase-2 expression in newborn pigs
Varga V, Németh J, Oláh O, Tóth-Szűki V, Kovács V, Remzső G, Domoki F. · Acta Pharmacologica Sinica. 2018;39(8):1273-1283.
The effect of hydrogen inhalation on temporary threshold shift following simultaneous exposure to noise and carbon monoxide in guinea pigs
Bagheri F, Pourbakht A, Raisi A, Kamali M, Faridan M. · Health Scope. 2018;7(4):e55353.
Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model.
Liu X, Ma C, Wang X, Wang W, Li Z, Wang X, Wang P, Sun W, Xue B. · 2017.
Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig
Fransson AE, Kisiel M, Pirttilä K, Pettersson C, Videhult Pierre P, Laurell GFE. · Frontiers in cellular neuroscience. 2017;11:280.
Inhaled hydrogen ameliorates endotoxin‐induced bowel dysfunction
Sakata H, Okamoto A, Aoyama-Ishikawa M, Yamashita H, Kohama K, Fujisaki N, Yamada T, Kotani J, Tsukahara K, Iida A, Nakao A. · 2017.
Molecular hydrogen increases resilience to stress in mice
Gao Q, Song H, Wang XT, Liang Y, Xi YJ, Gao Y, Guo QJ, LeBaron T, Luo YX, Li SC, Yin X, Shi HS, Ma YX. · Scientific reports. 2017;7(1):9625.
Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury Can Be Tracked in Vivo Using Molecular Imaging
Audi SH, Jacobs ER, Zhang X, Camara AKS, Zhao M, Medhora M, Rizzo B, Clough AV. · Shock. 2017;48(4):467-476.
Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model
Hong Y, Sun L, Sun R, Chen H, Yu Y, Xie K. · Experimental and Therapeutic Medicine. 2016;11(6):2590-2596.
Hydrogen does not exert neuroprotective effects or improve functional outcomes in rats after intracerebral hemorrhage
Takeuchi S, Nagatani K, Otani N, Wada K, Mori K. · Turk Neurosurg. 2016;26(6):854–859.
Hydrogen gas inhalation protects against liver ischemia/reperfusion injury by activating the NF-κB signaling pathway
Zhang CB, Tang YC, Xu XJ, Guo SX, Wang HZ. · Experimental and Therapeutic Medicine. 2015;9(6):2114-2120.
Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: a report of three cases
Ishibashi T, Ichikawa M, Sato B, Shibata S, Hara Y, Naritomi Y, Okazaki K, Nakashima Y, Iwamoto Y, Koyanagi S, Hara H, Nagao T. · Mol Med Rep. 2015;12(2):2757–2764.