Hydrogen inhalation attenuates oxidative-stress-related endothelial injury after subarachnoid hemorrhage in rats
Zhuang Z et al. · Front Neurosci. 2020;13:1441.
Inhaled molecular hydrogen research
Browse 184 source-checked molecular hydrogen records classified as inhaled hydrogen, with human and preclinical evidence separated.
184full-text-checked records
63human studies
121animal and laboratory records
No treatment conclusion is impliedAdministration routes, concentrations, doses and treatment schedules vary and must not be treated as interchangeable. Every result must be interpreted in the context of its design, population or model, intervention, comparator and measured outcome.
Hydrogen therapy can be used to control tumor progression and alleviate the adverse events of medications in patients with advanced non-small cell lung cancer.
Chen JB, Kong XF, Mu F, Lu TY, Lu YY, Xu KC. · Medical Gas Research. 2020;10:285560.
Hydrogen/oxygen mixed gas inhalation improves disease severity and dyspnea in patients with Coronavirus disease 2019 in a recent multicenter, open-label clinical trial
Guan WJ, Wei CH, Chen AL, Sun XC, Guo GY, Zou X, Shi JD, Lai PZ, Zheng ZG, Zhong NS. · Journal of Thoracic Disease. 2020;12(6):3448.
Impact of hydrogen-rich gas mixture inhalation through nasal cannula during post-exercise recovery period on subsequent oxidative stress, muscle damage, and exercise performances in men
Shibayama Y et al. · Med Gas Res. 2020;10(4):155–162.
Inhalation of molecular hydrogen increases breath acetone excretion during submaximal exercise: a randomized, single-blinded, placebo-controlled study
Hori A et al. · Med Gas Res. 2020;10(3):96–102.
Inhaled H_2 or CO_2 Do Not Augment the Neuroprotective Effect of Therapeutic Hypothermia in a Severe Neonatal Hypoxic-Ischemic Encephalopathy Piglet Model
Kovács V, Remzső G, Tóth-Szűki V, Varga V, Németh J, Domoki F. · 2020.
Low-Flow Nasal Cannula Hydrogen Therapy
Sano M et al. · J Clin Med Res. 2020;12(10):674–680.
Pharmacokinetics of a single inhalation of hydrogen gas in pigs
Sano M, Ichihara G, Katsumata Y, Hiraide T, Hirai A, Momoi M, Tamura T, Ohata S, Kobayashi E. · PloS one. 2020;15(6):e0234626.
Two weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence patients with advanced non-small cell lung cancer: a self-controlled study
Chen JB et al. · Med Gas Res. 2020;10(4):149–154.
A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation
Chen J, Mu F, Lu T, Ma Y, Du D, Xu K. · OncoTargets and therapy. 2019;12:8645-8651.
Aerosol inhalation of a hydrogen-rich solution restored septic renal function
Yao W, Guo A, Han X, Wu S, Chen C, Luo C, Li H, Li S, Hei Z. · Aging. 2019;11(24):12097-12113.
Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report
Chen J, Mu F, Lu T, Du D, Xu K. · OncoTargets and therapy. 2019;12:11145-11151.
Hydrogen Gas Alleviates Chronic Intermittent Hypoxia-Induced Renal Injury through Reducing Iron Overload
Guan P, Sun ZM, Luo LF, Zhao YS, Yang SC, Yu FY, Wang N, Ji ES. · Molecules (Basel, Switzerland). 2019;24(6):E1184.
Hydrogen gas distribution in organs after inhalation: Real-time monitoring of tissue hydrogen concentration in rat
Yamamoto R, Homma K, Suzuki S, Sano M, Sasaki J. · Scientific Reports. 2019;9:1255.
Hydrogen gas inhalation ameliorates lung injury after hemorrhagic shock and resuscitation
Moon DH, Kang DY, Haam SJ, Yumoto T, Tsukahara K, Yamada T, Nakao A, Lee S. · Journal of Thoracic Disease. 2019;11(4):1519–1527.
Hydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study
Camara R, Matei N, Camara J, Enkhjargal B, Tang J, Zhang JH. · Medical Gas Research. 2019;9(2):74–79.
Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report
Chen JB, Pan ZB, Du DM, Qian W, Ma YY, Mu F, Xu KC. · World journal of clinical cases. 2019;7(15):2065-2074.
Hydrogen inhalation protects hypoxic–ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats
Wu G, Chen Z, Wang P, Zhao M, Fujino M, Zhang C, Zhou W, Hirano SI, Li XK, Zhao L. · Experimental Biology and Medicine. 2019;244(12):1017-1027.
Hydrogen inhibits microglial activation and regulates microglial phenotype in a mouse middle-cerebral-artery-occlusion model
Huang JL et al. · Med Gas Res. 2019;9(3):144–150.
Hydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model.
Htun Y, Nakamura S, Nakao Y, Mitsuie T, Nakamura M, Yamato S, Jinnai W, Koyano K, Ohta K, Morimoto A, Wakabayashi T, Sugino M, Fujioka K, Kato I, Kondo S, Yasuda S, Miki T, Ueno M, Kusaka T. · 2019.
Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest
Huang L, Applegate RL II, Applegate PM, Gong L, Ocak U, Boling W, Zhang JH. · Medical Gas Research. 2019;9(3):122–126.
Inhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection
Malý O, Zajak J, Hyšpler R, Turek Z, Astapenko D, Jun D, Váňová N, Kohout A, Radochová V, Kotek J, Páral J. · Annals of Translational Medicine. 2019;7(23):774.
Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation
Liu MY et al. · Stem Cell Res Ther. 2019;10:145.
Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression
Long P, Yan W, He M, Zhang Q, Wang Z, Li M, Xue J, Chen T, An J, Zhang Z. · BMC ophthalmology. 2019;19(1):112.