Independent research library

Molecular hydrogen (H2) research library

Explore 665 full-text-checked human, animal and laboratory studies on molecular hydrogen (H2), with methods, reported findings and limitations clearly separated.

665full-text-checked records

193human studies

472animal and laboratory records

How to interpret this libraryA study record reports what a source states and what was extracted from the complete available text. Inclusion is not proof of effectiveness, safety or clinical suitability. Human and preclinical evidence, clinical outcomes and biomarkers remain distinct.

665 matching records · page 4 of 28

PreclinicalInhaled H₂2025

Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study

Tanaka Y, Matsumura Y, Hayashi Y, Aoki M, Izawa Y, Endo K, Mato T. · Acute medicine & surgery. 2025;12(1):e70072.

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PreclinicalOther forms2025

Hydrogen rescues vascular endothelial cells in obstructive sleep apnea-hypopnea syndrome by modulating nitric oxide

Chen Q, Jiang D, He J, Sun M. · Journal of thoracic disease. 2025;17(11):9598-9609.

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HumanH₂-rich water2025

Hydrogen water versus normal saline for post-surgical irrigation: A study on healing and complication rates after third molar extraction

Devi H, S P IK, Ramesh N, S U A, R S AK, Selvaraj S. · Bioinformation. 2025;21(11):4148-4152.

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PreclinicalOther forms2025

Hydrogen-Generating Magnesium Alloy Seed Strand Sensitizes Solid Tumors to Iodine-125 Brachytherapy.

Hu P, Lin L, Chen G, Liu D, Guo H, Xiao M, Zhong Z, Yang G, Xu B, Huang D, Peng S, Li Y, Zhang Y, Huang T, Zhang F. · Advanced Science. 2025;12:2412263.

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HumanInhaled H₂2025

Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis

Wang C et al. · Front Pharmacol. 2025;16:1505922.

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PreclinicalOther forms2025

Hydrogen-Releasing Micromaterial Dressings: Promoting Wound Healing by Modulating Extracellular Matrix Accumulation Through Wnt/β-Catenin and TGF-β/Smad Pathways

Zhao P, Li Y, Guo B, Liu Z, Zhang X, Liu M, Ma X. · Pharmaceutics. 2025;17(3):279.

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HumanH₂-rich water2025

Hydrogen-rich electrolyzed water is a useful mouthwash due to its biofilm-control properties: an in vitro and in vivo study

Youn HY, Kim JH, Cho MJ, Hong SH, Kim EK. · Journal of Yeungnam medical science. 2025;42:34.

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PreclinicalOther forms2025

Hydrogen-Rich Saline Combined With Vacuum Sealing Drainage Promotes Wound Healing by Altering Biotin Metabolism

Kuang X, Liang Z, Xia Y, Shan M, Hao Y, Liu H, Wang Z, He Q, Xia C, Feng C, Chang G, Wang Y. · Journal of Cellular and Molecular Medicine. 2025;29(1):e70292.

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PreclinicalH₂-rich water2025

Hydrogen-Rich Water Attenuates Diarrhea in Weaned Piglets via Oxidative Stress Alleviation

Zhang P, Yang J, Lu Z, Liang Q, Yang X, Wang J, Guo J, Zhao Y. · Biology. 2025;14(8):997.

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PreclinicalH₂-rich water2025

Hydrogen-rich water attenuates radiation-induced oral mucositis in mice via antioxidant and gut microbiota-stabilizing effects: a longitudinal study

Lan Z et al. · Gut Microbes Rep. 2025;2(1):2595392.

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HumanH₂-rich water2025

Hydrogen-Rich Water Decreases Muscle Damage and Improves Power Endurance in Elite Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial

Ogannisyan M et al. · J Lifestyle Med. 2025;15(1):8–17.

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PreclinicalH₂-rich water2025

Hydrogen-Rich Water Potentiates Cannabinoid- and Gabapentinoid-Induced Analgesia in Neuropathic Pain

Tort NA, Negrini-Ferrari SE, Pol O. · International journal of molecular sciences. 2025;26(24):12155.

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HumanOther forms2025

Immunomodulatory Effects of Molecular Hydrogen Therapy in Systemic Lupus Erythematosus With Pericarditis and Pleuritis: A Case Report

Tu TH, Lu JW, Ho YJ, Lui SW, Hsieh TY, Wang KY, Liu FC. · In vivo (Athens, Greece). 2025;39(5):3014-3024.

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PreclinicalH₂-rich water2025

Long-term administration of hydrogen-rich water enhances quality of life in diabetic rats and reduces renal neoplasm incidence through modulation of inflammatory and metabolic pathways

Chen Q, Yu S, Pan Y, Tang H, Wang Y, Feng N, Wu H, Yu G. · Translational andrology and urology. 2025;14(6):1765-1781.

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PreclinicalH₂-rich water2025

Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice

He Q et al. · PLoS One. 2025;20(2):e0317080.

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PreclinicalH₂-rich water2025

Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights

Xu K, Liu H, Wang Y, He Y, Liu M, Lu H, Wang Y, Niu P, Qin X. · Antioxidants (Basel, Switzerland). 2025;14(8):948.

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PreclinicalOther forms2025

Molecular Hydrogen Affords Similar Neuroprotection to Therapeutic Hypothermia in a Porcine Model of Neonatal Hypoxic–Ischemic Encephalopathy

Balog E, Remzső G, Tóth-Szűki V, Rózsa É, Kovács V, Domoki F. · Antioxidants (Basel, Switzerland). 2025;14(12):1405.

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PreclinicalH₂-rich water2025

Molecular hydrogen ameliorates anti-desmoglein 1 antibody-induced pemphigus-associated interstitial lung disease by inhibiting oxidative stress

Tang C et al. · Int J Mol Sci. 2025;26(9):4203.

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HumanOther forms2025

Molecular Hydrogen as a Potential Adjunctive Therapy to Improve Renal Function and Reduce Fatigue in an Elderly Patient With Chronic Comorbidities: A Case Report

Lin YT, Lu JW, Ho YJ, Lui SW, Hsieh TY, Wang KY, Liu FC. · In vivo (Athens, Greece). 2025;39(1):572-576.

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PreclinicalInhaled H₂2025

Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption

Pascal-Moussellard V, Alcaraz JP, Tanguy S, Salomez-Ihl C, Cinquin P, Boucher F, Boucher E. · Scientific reports. 2025;15(1):11482.

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HumanOther forms2025

Molecular Hydrogen as an Adjuvant Therapy in Comorbid Sjögren’s Syndrome, SLE, and ILD: A Case Report on Immune Modulation and Fatigue Reduction

Tsai YH, Lu JW, Tu JI, Li YJ, Hsu HF, Chang FH, Ho YJ, Lui SW, Hsieh TY, Wang KY, Liu FC. · In vivo (Athens, Greece). 2025;39(4):2228-2235.

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HumanOther forms2025

Molecular Hydrogen as an Adjuvant Therapy in Severe Lupus Serositis With Heart Failure: A Case Report on Immune Modulation and Fatigue Reduction

Lin YT, Lu JW, Ho YJ, Lui SW, Hsieh TY, Liu HC, Wang KY, Liu FC. · In vivo (Athens, Greece). 2025;39(2):1200-1206.

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PreclinicalInhaled H₂2025

Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism

Tian Y, Su H, Chen Y, Geng X, Zhang Y, Wang Y, Tang W, Fan W, Zhou J, Wei Y. · Molecular biology reports. 2025;52(1):751.

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HumanOther forms2025

Molecular Hydrogen Capsule Therapy for Primary Biliary Cholangitis With Elevated IgG4: A Case Report on Immune Marker Normalization

Lin YT, Lu JW, Lin JC, Ho YJ, Lui SW, Hsieh TY, Liu HC, Wang KY, Liu FC. · In vivo (Athens, Greece). 2025;39(3):1669-1675.

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