Independent research library

Molecular hydrogen (H2) research library

Explore 665 full-text-checked human, animal and laboratory studies on molecular hydrogen (H2), with methods, reported findings and limitations clearly separated.

665full-text-checked records

193human studies

472animal and laboratory records

How to interpret this libraryA study record reports what a source states and what was extracted from the complete available text. Inclusion is not proof of effectiveness, safety or clinical suitability. Human and preclinical evidence, clinical outcomes and biomarkers remain distinct.

665 matching records · page 7 of 28

PreclinicalInhaled H₂2024

High‐concentration hydrogen inhalation mitigates sepsis‐associated encephalopathy in mice by improving mitochondrial dynamics

Cui Y, Meng S, Zhang N, Liu J, Zheng L, Ma W, Song Y, Wang Z, Shen Y, Liu J, Xie K. · CNS neuroscience & therapeutics. 2024;30(9):e70021.

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PreclinicalH₂-rich water2024

Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes.

Li H, Sun H, Li S, Huang L, Zhang M, Wang S, Liu Q, Ying J, Zhao F, Su X, Mu D, Qu Y. · 2024.

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PreclinicalOther forms2024

Hydrogen gas improves proliferation and mitochondrial activity of human adipose-derived stem cells after cryopreservation

Kimura K, Tabata Y. · Regenerative therapy. 2024;26:571-577.

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PreclinicalInhaled H₂2024

Hydrogen Gas Inhalation Alleviates Airway Inflammation and Oxidative Stress on Ovalbumin-Induced Asthmatic BALB/c Mouse Model

He W, Rahman MH, Bajgai J, Abdul-Nasir S, Mo C, Ma H, Goh SH, Bomi K, Jung H, Kim CS, Lee H, Lee KJ. · Antioxidants (Basel, Switzerland). 2024;13(11):1328.

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PreclinicalInhaled H₂2024

Hydrogen gas inhalation ameliorates LPS-induced BPD by inhibiting inflammation via regulating the TLR4–NFκB–IL6/NLRP3 signaling pathway in the placenta

Zhang Y, Ren X, Zhang L, Sun X, Li W, Chen Y, Tian Y, Chu Z, Wei Y, Yao G, Wang Y. · European journal of medical research. 2024;29(1):285.

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HumanInhaled H₂2024

Hydrogen gas inhalation prior to high-intensity training reduces attenuation of nitric oxide bioavailability in male rugby players

Zhao Y, Li C, Zhou S, Xu Z, Huang X, Wen L. · PeerJ. 2024;12:e18503.

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PreclinicalInhaled H₂2024

Hydrogen gas inhalation therapy may not work sufficiently to mitigate oxidative stress induced with REBOA

Matsumura Y, Hayashi Y, Aoki M, Izawa Y. · Scientific reports. 2024;14(1):32128.

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PreclinicalInhaled H₂2024

Hydrogen Gas Inhalation Treatment for Coronary Artery Lesions in a Kawasaki Disease Mouse Model

Shih WL, Yeh TM, Chen KD, Leu S, Liu SF, Huang YH, Kuo HC. · Life (Basel, Switzerland). 2024;14(7):796.

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HumanInhaled H₂2024

Hydrogen inhalation: A novel approach to alleviating allergic rhinitis symptoms by modulating nasal flora^[☆]

Wang N, Ma Q, Zhai J, Che Y, Liu J, Tang T, Sun Y, Wang J, Yang W. · The World Allergy Organization journal. 2024;17(10):100970.

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PreclinicalInhaled H₂2024

Hydrogen therapy promotes macrophage polarization to the M2 subtype in radiation lung injury by inhibiting the NF-κB signalling pathway

Gao X, Niu S, Li L, Zhang X, Cao X, Zhang X, Pan W, Sun M, Zhao G, Zheng X, Song G, Zhang Y. · Heliyon. 2024;10(10):e30902.

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PreclinicalOther forms2024

Hydrogen Therapy Reverses Cancer‐Associated Fibroblasts Phenotypes and Remodels Stromal Microenvironment to Stimulate Systematic Anti‐Tumor Immunity

Meng X, Liu Z, Deng L, Yang Y, Zhu Y, Sun X, Hao Y, He Y, Fu J. · Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024;11(28):e2401269.

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PreclinicalOther forms2024

Hydrogen treatment reduces electroencephalographic activity and neuronal death in rats with refractory status epilepticus by inhibiting membrane NR2B phosphorylation and oxidative stress

Jia R, Zhu G, Zhao R, Li T, Jiang W, Cui X. · The Journal of international medical research. 2024;52(3):3000605241235589.

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PreclinicalOther forms2024

Hydrogen-rich alkaline water supplementation restores a healthy state and redox balance in H₂O₂-treated mice

Mizzoni D, Logozzi M, Di Raimo R, Spada M, Fais S. · Int J Mol Sci. 2024;25(12):6736.

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HumanInhaled H₂2024

Hydrogen-Rich Gas Enhanced Sprint-Interval Performance: Metabolomic Insights into Underlying Mechanisms

Dong G, Liu H, Chen Y, Bao D, Xu W, Zhou J. · Nutrients. 2024;16(14):2341.

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PreclinicalOther forms2024

Hydrogen-rich solution alleviates acute radiation pneumonitis by regulating oxidative stress and macrophages polarization

Yin Z, Xu W, Ling J, Ma L, Zhang H, Wang P. · Journal of radiation research. 2024;65(3):291-302.

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PreclinicalH₂-rich water2024

Hydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells

Tsou SH, Lin SC, Chen WJ, Hung HC, Liao CC, Kornelius E, Huang CN, Lin CL, Yang YS. · Biomedicines. 2024;12(7):1444.

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PreclinicalH₂-rich water2024

Hydrogen-rich water alleviates constipation by attenuating oxidative stress through the sirtuin1/nuclear factor-erythroid-2-related factor 2/heme oxygenase-1 signaling pathway

Chen KD, Wang KL, Chen C, Zhu YJ, Tang WW, Wang YJ, Chen ZP, He LH, Chen YG, Zhang W. · World J Gastroenterol. 2024;30(20):2709–2725.

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PreclinicalH₂-rich water2024

Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice

Vincent SM et al. · Sleep Adv. 2024;5(1):zpad057.

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HumanH₂-rich water2024

Hydrogen-rich water supplementation promotes muscle recovery after two strenuous training sessions performed on the same day in elite fin swimmers

Sládečková B et al. · Front Physiol. 2024;15:1321160.

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PreclinicalOther forms2024

Inhalation of hydrogen gas protects against mitomycin-induced pulmonary veno-occlusive disease

Zhang C et al. · Respir Res. 2024;25:281.

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PreclinicalOther forms2024

Molecular hydrogen and extracorporeal gas exchange: a match made in heaven? An in vitro pilot study

Mouzakis FL, Hima F, Kashefi A, Greven J, Rink L, van der Vorst EPC, Jankowski J, Mottaghy K, Spillner J. · Biomedicines. 2024;12(8):1883.

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HumanOther forms2024

Molecular Hydrogen as a Promising Therapy Could Be Linked With Increased Resting Treg Cells or Decreased Fas+ T Cell Subsets in a IgG4-PF-ILD Patient: A Case Report

Lui SW, Lu JW, Ho YJ, Tang SE, Ko KH, Hsieh TY, Liu FC. · In Vivo. 2024;38(3):1512-1518.

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PreclinicalInhaled H₂2024

Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy

Cui Y, Li Y, Meng S, Song Y, Xie K. · BMC anesthesiology. 2024;24(1):72.

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HumanH₂-rich water2024

Molecular Hydrogen for Outpatients with COVID-19 (Hydro-COVID): A Phase 3 Randomised, Triple-Blinded, Pragmatic, Placebo-Controlled, Multicentre Trial

Gaboreau Y et al. · J Clin Med. 2024;13(15):4308.

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