Independent research library

Molecular hydrogen (H2) research library

Explore 665 full-text-checked human, animal and laboratory studies on molecular hydrogen (H2), with methods, reported findings and limitations clearly separated.

665full-text-checked records

193human studies

472animal and laboratory records

How to interpret this libraryA study record reports what a source states and what was extracted from the complete available text. Inclusion is not proof of effectiveness, safety or clinical suitability. Human and preclinical evidence, clinical outcomes and biomarkers remain distinct.

665 matching records · page 23 of 28

PreclinicalOther forms2017

Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis

Dong WW, Zhang YQ, Zhu XY, Mao YF, Sun XJ, Liu YJ, Jiang L. · Medical science monitor : international medical journal of experimental and clinical research. 2017;23:2357-2364.

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PreclinicalOther forms2017

Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis

Li J, Ge Z, Fan L, Wang K. · BMC musculoskeletal disorders. 2017;18(1):58.

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PreclinicalOther forms2017

The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against N -Methyl- N -Nitrosourea Induced Retinal Degeneration: A Topographic Study

Tao Y, Chen T, Fang W, Yan Z, Yang Q, Huang Y, Yu L, Fan L. · Frontiers in pharmacology. 2017;8:587.

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PreclinicalOther forms2017

The reason for the amelioration of N-methyl-N-nitrosourea-induced retinitis pigmentosa in rats by hydrogen-rich saline

Yan WM, Chen T, Wang XC, Qi LS, Zhao GH, Yang GQ, Ma YF, Tao Y, Zhang L, Zhang ZM. · International Journal of Ophthalmology. 2017;10(10):1495-1503.

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PreclinicalH₂-rich water2017

Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage

Cejka C, Kossl J, Hermankova B, Holan V, Kubinova S, Zhang JH, Cejkova J. · Scientific reports. 2017;7(1):18017.

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PreclinicalOther forms2017

Therapeutic effects of hydrogen on chronic graft-versus-host disease

Qian L, Liu X, Shen J, Zhao D, Yin W. · Journal of Cellular and Molecular Medicine. 2017;21(10):2627–2630.

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PreclinicalInhaled H₂2016

Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model

Hong Y, Sun L, Sun R, Chen H, Yu Y, Xie K. · Experimental and Therapeutic Medicine. 2016;11(6):2590-2596.

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PreclinicalH₂-rich water2016

Effects of hydrogen-rich water on depressive-like behavior in mice

Zhang Y et al. · Sci Rep. 2016;6:23742.

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PreclinicalInhaled H₂2016

Hydrogen does not exert neuroprotective effects or improve functional outcomes in rats after intracerebral hemorrhage

Takeuchi S, Nagatani K, Otani N, Wada K, Mori K. · Turk Neurosurg. 2016;26(6):854–859.

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HumanH₂-rich water2016

Hydrogen water reduces NSE, IL-6, and TNF-α levels in hypoxic-ischemic encephalopathy

Yang L, Li D, Chen S. · Open medicine (Warsaw, Poland). 2016;11(1):399-406.

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PreclinicalOther forms2016

Hydrogen-rich saline attenuates cardiac and hepatic injury in a doxorubicin rat model by inhibiting inflammation and apoptosis

Gao Y et al. · Mediators Inflamm. 2016;2016:1320365.

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PreclinicalOther forms2016

Hydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model

Huang SL, Jiao J, Yan HW. · Experimental and Therapeutic Medicine. 2016;11(1):177-182.

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PreclinicalOther forms2016

Hydrogen-rich saline promotes recovery of renal function after ischemia-reperfusion injury in rats via anti-apoptosis and anti-inflammation

Li Y et al. · Front Pharmacol. 2016;7:106.

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PreclinicalOther forms2016

Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice

Liu Q, Li BS, Song YJ, Hu MG, Lu JY, Gao A, Sun XJ, Guo XM, Liu R. · Mol Med Rep. 2016;13(4):3588–3596.

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PreclinicalH₂-rich water2016

Hydrogen-rich water exerting a protective effect on ovarian reserve function in a mouse model of immune premature ovarian failure induced by zona pellucida 3

He X, Wang SY, Yin CH, Wang T, Jia CW, Ma YM. · Chinese Medical Journal. 2016;129(19):2331–2337.

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PreclinicalH₂-rich water2016

Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model

Tamaki N, Orihuela-Campos RC, Fukui M, Ito HO. · Oxidative medicine and cellular longevity. 2016;2016:5679040.

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PreclinicalOther forms2016

Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress

Meng J, Yu P, Jiang H, Yuan T, Liu N, Tong J, Chen H, Bao N, Zhao J. · American Journal of Translational Research. 2016;8(10):4472–4477.

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PreclinicalOther forms2016

Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators

Iuchi K, Imoto A, Kamimura N, Nishimaki K, Ichimiya H, Yokota T, Ohta S. · Scientific reports. 2016;6:18971.

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PreclinicalH₂-rich water2016

Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism

Kamimura N, Ichimiya H, Iuchi K, Ohta S. · NPJ Aging and Mechanisms of Disease. 2016;2:16008.

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PreclinicalH₂-rich water2016

Molecular hydrogen suppresses activated Wnt/β-catenin signaling

Lin Y, Ohkawara B, Ito M, Misawa N, Miyamoto K, Takegami Y, Masuda A, Toyokuni S, Ohno K. · Scientific reports. 2016;6:31986.

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PreclinicalOther forms2016

Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression

Li Q, Yu P, Zeng Q, Luo B, Cai S, Hui K, Yu G, Zhu C, Chen X, Duan M, Sun X. · Neurochemical research. 2016;41(10):2655-2665.

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PreclinicalH₂-rich water2016

New Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State

Franceschelli S, Gatta DM, Pesce M, Ferrone A, Patruno A, de Lutiis MA, Grilli A, Felaco M, Croce F, Speranza L. · International journal of molecular sciences. 2016;17(9):E1461.

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PreclinicalH₂-rich water2016

Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice

Guo J, Zhao D, Lei X, Zhao H, Yang Y, Zhang P, Liu P, Xu Y, Zhu M, Liu H, Chen Y, Chuai Y, Li B, Gao F, Cai J. · 2016.

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PreclinicalOther forms2016

Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis

Zhou HX, Han B, Hou LM, An TT, Jia G, Cheng ZX, Ma Y, Zhou YN, Kong R, Wang SJ, Wang YW, Sun XJ, Pan SH, Sun B. · PloS one. 2016;11(4):e0154483.

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